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Webinar
Now available on-demand
New Technologies to Streamline Chemical Imaging and Quantification of API Forms in Drug Development

This webinar will describe the use of molecular spectroscopy techniques (Raman and IR) for solid-state analysis in drug development. Two presentations will focus on chemical imaging of polymorphs by LDIR, and the rapid quantification of low level crystalline forms using transmission Raman.

Read More thumbnail image: <font color=red>Webinar<br/>Now available on-demand<br/></font>New Technologies to Streamline Chemical Imaging and Quantification of API Forms in Drug Development

Webinar
Now available on-demand
Leak Detection of Biopharmaceutical Processes- How to Avoid Costly Contamination

In this webinar, production process and quality managers, engineers and technicians will learn how to easily avoid very costly contamination and lost production batches.

Read More thumbnail image: <font color=red>Webinar<br/>Now available on-demand<br/></font>Leak Detection of Biopharmaceutical Processes- How to Avoid Costly Contamination

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Shimadzu Europa
Automatic Pre-Column Derivatization of Amino Acids by LC

thumbnail image: <font size=3>Shimadzu Europa</font><br />Automatic Pre-Column Derivatization of Amino Acids by LC

Amino acids as building blocks of peptides and proteins are present in animals, humans and plants. The analysis of amino acids is of essential significance in several areas including food science, clinical diagnostic and pharmaceutical products research. The classical LC determination of amino acids is performed by the sample pretreatment including pre-column as well as post-column derivatization increasing or even enabling spectroscopic detection.

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Ezines

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The preparative chromatography of biomolecules, such as proteins, typically requires extensive offline analysis of the fractions before fraction pooling and subsequent processing can begin. Scientists from the Austrian Centre of Industrial Biotechnology, the University of Natural Resources and Life Sciences, and Boehringer Ingelheim (Vienna) examined the output from the chromatographic purification of a protein using a large number of different online detectors and constructed suitable models for...

Quick chromatography characterises coconut compounds

Ryan De Vooght-Johnson

May 21, 2019

thumbnail image: Quick chromatography characterises coconut compounds

The complex mixtures of compounds found in bio-oil samples are often separated by two-dimensional GC (GC × GC), usually involving long run times. Scientists from three Brazilian universities (the Federal University of Rio Grande do Sul, Porto Alegre, Tiradentes University, Aracaju, and the State University of Rio de Janeiro) developed a new, quicker method for bio-oil chromatography using fast GC × GC with a cryogen-free thermal modulator, using it to examine a bio-oil produced from the pyrolysis of...

The hypothetical human glucuronide metabolite of ethylene glycol (EG) has been detected and measured in serum of patients with EG poisoning by LC/MS and has been proposed as a biomarker for EG intake.

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Education

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The Basics of Micro-LC

Thorsten Teutenberg, Terence Hetzel, Denise Loeker, Juri Leonhardt

Apr 3, 2018

thumbnail image: The Basics of Micro-LC

For some time “sustainable processes” has been the phrase on everyone’s lips. As far as analytical labs are concerned there are many possibilities for saving energy or rather for using resources more efficiently. Besides the real “energy guzzlers” such as extractors and safety cabinets, complex analysis apparatus has to be subjected to critical system checks, too.

Selected key technologies of the analytical science industry are discussed by Steve Down with reference to burgeoning application areas and the scope for future improvements.

Ion source pressure plays a significant role in the process of ionization and the subsequent ion transmission inside a mass spectrometer. Pressurizing the ion source to a gas pressure greater than atmospheric pressure is a relatively new approach that aims to further improve the performance of atmospheric pressure ionization sources. A brief review on the development of super-atmospheric pressure ion sources, including high-pressure electrospray, field desorption and superheated ESI, and the strategies to...

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Journals

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Radiation and Health is a specialty section of Frontiers in Public Health.

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