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Developments in Analysis of Drugs and Metabolites in Skeletal Remains

Bone remains are one of the least characterized and most challenging matrices for forensic toxicological analysis. Before the forensic utility of the matrix may be fully realized, controlled experiments must be carried out. This presentation will highlight the value that UPLC-based approaches have brought to the drug analysis of bone samples. In addition, we will discuss the most recent findings in analytical developments using UPLC-QTof mass spectrometry, including: dramatic enhancements in sensitivity,...

Read More thumbnail image: <font color=red>Webinar<br/>Now available on-demand</font><br/>Developments in Analysis of Drugs and Metabolites in Skeletal Remains

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Now available on-demand

Peptide Hormones in Sports Drug Testing: Detection of Emerging Protein/Peptide Based Drugs by Means of LC-MS

Therapeutic proteins and peptides have emerged as one of the most important classes of new pharmaceuticals. Several drug candidates with potential performance-enhancing properties are currently in preclinical or clinical development. The current version of the WADA Prohibited List includes a variety of protein/peptide-based doping agents, some of which can be detected in biological samples by using immunological and mass spectrometry-based approaches.

Read More thumbnail image: <font color=red>Webinar<br/>Now available on-demand</font><br/>Peptide Hormones in Sports Drug Testing: Detection of Emerging Protein/Peptide Based Drugs by Means of LC-MS

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2017 Edition of Mass Spectra of Designer Drugs

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Available now from Wiley and Wiley-VCH, the 2017 edition of Mass Spectra of Designer Drugs

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Ezines

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Two specific liquid chromatography-tandem mass spectrometry methods have been developed for the analysis of nandrolone and ractopamine in veal calf urine, both including hydrolysis of the corresponding conjugates.

Korean chemists have used a bi-polar carboxen-polydimethylsiloxane fiber to extract volatile organic compounds from urine, prior to analysis by gas chromatography/mass spectrometry.

By combining thin-layer chromatography with a magnetic field, Polish chemists have developed a novel method for determining the lipophilicity of complexes of carboxylates with transition metals or rare earth elements.

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Education

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Selected key technologies of the analytical science industry are discussed by Steve Down with reference to burgeoning application areas and the scope for future improvements.

Ion source pressure plays a significant role in the process of ionization and the subsequent ion transmission inside a mass spectrometer. Pressurizing the ion source to a gas pressure greater than atmospheric pressure is a relatively new approach that aims to further improve the performance of atmospheric pressure ionization sources. A brief review on the development of super-atmospheric pressure ion sources, including high-pressure electrospray, field desorption and superheated ESI, and the strategies to...

In the current context of international conflicts and localized terrorist actions, there is unfortunately a permanent threat of attacks with unconventional warfare agents. Among these, biological agents such as toxins, microorganisms, and viruses deserve particular attention owing to their ease of production and dissemination. Mass spectrometry-based techniques for the detection and quantification of biological agents have a decisive role to play for countermeasures in a scenario of biological attacks.

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Events

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Future Events

HPLC 2017

Jun 18, 2017

Prague, Czech Republic

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The HPLC 2017 Prague symposium is organized for the first time in the Czech Republic. The HPLC symposium series is well known as the world leading forum for the information exchange among researchers dealing with separations in liquid phases and supercritical fluids.

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Journals

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Radiation and Health is a specialty section of Frontiers in Public Health.

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Videos

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Waters Empower Cloud

Date: Mar 8, 2017

Thomas Tucker from Waters Corporation discusses Empower Cloud, a cloud deployable, compliance ready enterprise Chromatography Data Software (CDS).

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