Therapeutic proteins and peptides have emerged as one of the most important classes of new pharmaceuticals. Several drug candidates with potential performance-enhancing properties are currently in preclinical or clinical development. The current version of the WADA Prohibited List includes a variety of protein/peptide-based doping agents, some of which can be detected in biological samples by using immunological and mass spectrometry-based approaches.Read More
With global concerns about food quality and food safety continuing to garner attention, it is important for both manufacturers and regulatory bodies to have robust analytical instrumentation and methods to ensure accurate and precise results. For the measurement of inorganic elements and nutrients, sample preparation can be of critical importance to the quality of the analysis. Here we discuss the process of sample preparation and analysis, tools and techniques for the measurement of inorganic elements in...Read More
HPLC and UHPLC as well as SFC systems can analyze substances quantitatively in mixtures containing multiple components by separating and detecting target substances. They are used to separate, quantify, qualify or purify single components from a sample containing various analytes in different matrices. Shimadzu offers a wide variety of application-specific systems such as automated sample pretreatment systems for amino acid analysis or on-line sample trapping for the quantification of residual pesticides...Read More
Dec 2, 2016
Toxins that have been added to foods as chemical and biological warfare agents can be detected using a novel proteomics approach which bypasses the need for antibody-based isolation by employing isotope-labelled versions of the toxins.
Ryan De Vooght-Johnson
Dec 1, 2016
Whether we love or loathe tobacco, we have to accept that analysis of tobacco volatiles is an important topic, both for the industry and medical investigations. Scientists from China Tobacco and Zhejiang University have developed a novel method of isolating volatile components from tobacco, the data from which allowed the grouping of various tobacco samples into three distinct classes, corresponding to ‘fresh’, ‘moderate’ and ‘rich’ styles.
Ryan De Vooght-Johnson
Dec 1, 2016
Microscopic diatoms may be small, but these silica-clad plankton have their own chemical weapons, producing compounds, such as polyunsaturated aldehydes, that inhibit some of their predators. Scientists from Jena University in Germany have produced an improved method for detecting such compounds, using modern ultra-high performance liquid chromatography.View All Ezines
Nov 25, 2016
Ion source pressure plays a significant role in the process of ionization and the subsequent ion transmission inside a mass spectrometer. Pressurizing the ion source to a gas pressure greater than atmospheric pressure is a relatively new approach that aims to further improve the performance of atmospheric pressure ionization sources. A brief review on the development of super-atmospheric pressure ion sources, including high-pressure electrospray, field desorption and superheated ESI, and the strategies to...
Nov 16, 2016
In the current context of international conflicts and localized terrorist actions, there is unfortunately a permanent threat of attacks with unconventional warfare agents. Among these, biological agents such as toxins, microorganisms, and viruses deserve particular attention owing to their ease of production and dissemination. Mass spectrometry-based techniques for the detection and quantification of biological agents have a decisive role to play for countermeasures in a scenario of biological attacks.
Nov 21, 2014
We are proud to announce a new series of educational webinars run in collaboration with Chromedia, COAST, and SciMind, a product of the American Chemical Society. These webinars will build into a must-have set of tutorial materials for the analytical scientist.View All Education Articles
Mar 5, 2017
Atlanta, GA, United States
Pittcon 2017, the world’s largest annual conference and exposition for laboratory science, March 5-9, 2017, Chicago, IL. Pittcon offers the latest innovations from exhibitors from around the world, unique networking opportunities with world renowned scientists, and exceptional educational opportunities.
Date: Dec 6, 2016 - 15:00
Bone remains are one of the least characterized and most challenging matrices for forensic toxicological analysis. Before the forensic utility of the matrix may be fully realized, controlled experiments must be carried out. This presentation will highlight the value that UPLC-based approaches have brought to the drug analysis of bone samples. In addition, we will discuss the most recent findings in analytical developments using UPLC-QTof mass spectrometry, including: dramatic enhancements in sensitivity,...
Mark F. Vitha
Oct 21, 2016
Oct 11, 2016
Gerhardus de Jong
Aug 3, 2016
Nov 29, 2016
Nov 29, 2016
Nov 14, 2016
SCIEX has donated US$11,000 to the World Cancer Research Fund, a UK-based charity that funds and supports vital scientific research into cancer prevention related to diet, weight and physical activity.
Date: Jun 16, 2016
Aaron Bailey from Thermo Fisher Scientific introduces us to the new Q Exactive HF for Biopharma at ASMS 2016.