EarlyView Articles

Skip to Navigation

The very latest articles from the scientific literature
on Wiley Online Library...


You can keep up-to date on these EarlyView articles, which focus on spectroscopy
and separation science:

Earlyview RSS Feed

rss

Filter by Journal

Browse By Journal

Application of an activity‐based receptor bioassay to investigate the in vitro activity of selected indole‐ and indazole‐3‐carboxamide‐based synthetic cannabinoids at CB1 and CB2 receptors

Published: Nov 18, 2018

Author(s): Carolina Noble, Annelies Cannaert, Kristian Linnet, Christophe P. Stove

Journal: Drug Testing and Analysis

Abstract Synthetic cannabinoids (SCs) are the most chemically diverse group of new psychoactive substances. This group has been associated with several intoxications, many with fatal outcomes. Although advancements have been achieved in pharmacology, metabolism, and detection of these compounds in recent years, these aspects are still unresolved for many SCs. The aim of this study was to investigate the in vitro potency of 14...

Read More thumbnail image: Application of an activitybased receptor bioassay to investigate the in vitro activity of selected indole and indazole3carboxamidebased synthetic cannabinoids at CB1 and CB2 receptors

Rapid analysis of Na, Mg, Ca, Fe, and Zn in breakfast cereals (granola type) by energy dispersive‐X‐ray fluorescence

Published: Nov 18, 2018

Author(s): Loïc Perring, Aurélien Cotard, Sarah Al Sayadi, Stéphane Berrut

Journal: X-Ray Spectrometry

Energy dispersive‐X‐ray fluorescence (ED‐XRF) is a well spread near‐line analytical technique, suitable for easy and rapid measurement of major elements and/or trace elements especially in many different food matrices. This study demonstrates the fitness for purpose of this method to ensure the correct addition of minerals during breakfast cereal production. Indeed, variations in process and in raw material compositions may lead to values...

Read More thumbnail image: Rapid analysis of Na Mg Ca Fe and Zn in breakfast cereals granola type by energy dispersiveXray fluorescence

Efficient variable selection algorithm adopting variance inflated resampling weight vector into model population analysis

Published: Nov 18, 2018

Author(s): Biswanath Mahanty

Journal: Journal of Chemometrics

Abstract Variable iterative space shrinkage approach (VISSA) is an important variable selection algorithm known for its improved accuracy and outcome stability in partial least squares (PLS) regression models. However, time efficiency of VISSA is not very promising. In this work, three strategies to inflate the variance of resampling weight vector (RWV) have been proposed to accelerate the space shrinkage in VISSA. The original RWV...

Read More thumbnail image: Efficient variable selection algorithm adopting variance inflated resampling weight vector into model population analysis

Class‐specific variable selection in high‐dimensional discriminant analysis through Bayesian Sparsity

Published: Nov 18, 2018

Author(s): Fanny Orlhac, Pierre‐Alexandre Mattei, Charles Bouveyron, Nicholas Ayache

Journal: Journal of Chemometrics

Abstract Although the ongoing digital revolution in fields such as chemometrics, genomics, or personalized medicine gives hope for considerable progress in these areas, it also provides more and more high‐dimensional data to analyze and interpret. A common usual task in those fields is discriminant analysis, which however may suffer from the high dimensionality of the data. The recent advances, through subspace classification or...

Read More thumbnail image: Classspecific variable selection in highdimensional discriminant analysis through Bayesian Sparsity

Evaluating sulfates and nitrates as enemies of the recent constructions: Spectroscopic and thermodynamical study

Published: Nov 18, 2018

Author(s): Héctor Morillas, Settakorn Upasen, Maite Maguregui, Iker Marcaida, Euler Gallego‐Cartagena, Marcos L.S. Oliveira, Luis F.O. Silva

Journal: Journal of Raman Spectroscopy

Abstract Salt crystallization is one of the major problems currently faced by the field of architecture and construction. Its effects are devastating to the extent that they may even lead to loss of material. Although many innovative and resistant materials have been developed in the last years, in most of the constructions, salt crystallization is a persistent problem. Salts crystallizations are formed by the dissolution and...

Read More thumbnail image: Evaluating sulfates and nitrates as enemies of the recent constructions Spectroscopic and thermodynamical study

Photothermal CH vibrational overtone detection by two‐color laser absorption

Published: Nov 18, 2018

Author(s): Marlon Diaz, Parashu R. Nyaupane, Ashley Diaz, Carlos E. Manzanares

Journal: Journal of Raman Spectroscopy

Abstract In this experiment, the thermal lens technique is used with a modified arrangement of three lasers to induce a two‐color absorption. Two‐pump lasers, a variable wavelength orange dye laser (588–617 nm), a single line blue laser (488 nm), and a single line probe yellow laser (568 nm) are employed. A comparison is made between the magnitude of the thermal lens signal obtained with a one pump laser versus two...

Read More thumbnail image: Photothermal CH vibrational overtone detection by twocolor laser absorption

Microchip gel electrophoretic analysis of perchloric acid‐soluble serum proteins in systemic inflammatory disorders

Published: Nov 16, 2018

Author(s): Lilla Makszin, Péter Kustán, Balázs Szirmay, Csilla Páger, Emerencia Mező, Krisztina I. Kalács, Vera Pászthy, Erzsébet Györgyi, Ferenc Kilár, Andrea Ludány, Tamás Kőszegi

Journal: ELECTROPHORESIS

Abstract Perchloric acid (PCA) precipitation is a well‐known method for the separation of heavily glycosylated proteins and for reducing the masking effect of major serum proteins. The aim of this study is to characterize PCA‐soluble serum proteins in healthy individuals and in patients with systemic inflammatory diseases, such as Crohn's disease and sepsis. A PCA precipitation protocol was prepared and adapted to the analytical...

Read More thumbnail image: Microchip gel electrophoretic analysis of perchloric acidsoluble serum proteins in systemic inflammatory disorders

3D Multilayered paper‐ and thread/paper‐based microfluidic devices for bioassays

Published: Nov 15, 2018

Author(s): Natalia M. Neris, Ricardo D. Guevara, Ariana Gonzalez, Frank A. Gomez

Journal: ELECTROPHORESIS

Abstract In this paper we describe the fabrication of novel 3D microfluidic paper‐based analytical devices (3D‐μPADs) and a 3D microfluidic thread/paper‐based analytical device (3D‐μTPAD) to detect glucose and BSA through colorimetric assays. The 3D‐μPAD and 3D‐μTPAD consisted of three (wax, heat pressed wax‐printed paper, single‐sided tape) and four (hole‐punched single‐sided tape, blank chromatography circles, heat‐pressed...

Read More thumbnail image: 3D Multilayered paper and threadpaperbased microfluidic devices for bioassays

XPS primary excitation spectra of Zn 2 p , Fe 2 p , and Ce 3 d from ZnO, α‐Fe 2 O 3 , and CeO 2

Published: Nov 15, 2018

Author(s): Nicolas Pauly, Francisco Yubero, Juan Pedro Espinós, Sven Tougaard

Journal: Surface and Interface Analysis

Metal oxides are important for current development in nanotechnology. X‐ray photoelectron spectroscopy(XPS) is a widely used technique to study the oxidation states of metals, and a basic understanding of the photoexcitation process is important to obtain the full information from XPS. We have studied core level excitations of Zn 2p, Fe 2p, and Ce 3d photoelectron emissions from ZnO, α‐Fe2O3, and CeO2. Using an effective energy‐differential XPS...

Read More thumbnail image: XPS primary excitation spectra of Zn 2 p  Fe 2 p  and Ce 3 d from ZnO Fe 2 O 3  and CeO 2

Highly sensitive and rapid determination of tacrolimus in peripheral blood mononuclear cells by liquid chromatography–tandem mass spectrometry

Published: Nov 14, 2018

Author(s): Soma Bahmany, Lucia E.A. Wit, Dennis A. Hesselink, Teun Gelder, Nauras M. Shuker, Carla Baan, Bart C.H. Nagel, Birgit C.P. Koch, Brenda C.M. Winter

Journal: Biomedical Chromatography

Abstract After solid organ transplantation, tacrolimus is given to prevent rejection. Therapeutic drug monitoring is used to reach target concentrations of tacrolimus in whole blood. Because the site of action of tacrolimus is the lymphocyte, and tacrolimus binds ~80% to erythrocytes, the intracellular tacrolimus concentration in lymphocytes is possibly more relevant. For this purpose, we aimed to develop, improve and validate a...

Read More thumbnail image: Highly sensitive and rapid determination of tacrolimus in peripheral blood mononuclear cells by liquid chromatographytandem mass spectrometry

Electromembrane extraction of verapamil and riluzole from urine and wastewater samples using a mixture of organic solvents as a supported liquid membrane: Study on electric current variations

Published: Nov 14, 2018

Author(s): Atyeh Rahimi, Saeed Nojavan

Journal: Journal of Separation Science

Abstract In this study, the application of a mixture of organic solvents as a supported liquid membrane for improving the efficiency of the electromembrane extraction procedure was investigated. The extraction process was followed by high‐performance liquid chromatography analysis of two model drugs (verapamil and riluzole). In this research, four organic solvents, including 1‐heptanol, 1‐octanol, 2‐nitrophenyl octyl ether, and...

Read More thumbnail image: Electromembrane extraction of verapamil and riluzole from urine and wastewater samples using a mixture of organic solvents as a supported liquid membrane Study on electric current variations

Accurate and sensitive determination of sildenafil, tadalafil, vardenafil, and avanafil in illicit erectile dysfunction medications and human urine by LC with quadrupole‐TOF‐MS/MS and their behaviors in simulated gastric conditions

Published: Nov 14, 2018

Author(s): Elif Öztürk Er, Belma Özbek, Sezgin Bakırdere

Journal: Journal of Separation Science

Abstract The widespread use of phosphodiesterase‐5 inhibitors has attracted broad attention of counterfeiters to develop illicit erectile products with inaccurate amounts, unknown toxicity, and purity of active ingredients. Correspondingly, intake of these products endangers consumer health and needs to be screened for precautionary actions to reduce this risk. Therefore, in this study, a sensitive and rapid analytical method has...

Read More thumbnail image: Accurate and sensitive determination of sildenafil tadalafil vardenafil and avanafil in illicit erectile dysfunction medications and human urine by LC with quadrupoleTOFMSMS and their behaviors in simulated gastric conditions

Critical evaluation of microextraction pretreatment techniques—Part 2: Membrane‐supported and homogenous phase based techniques

Published: Nov 14, 2018

Author(s): Martina Havlikova, Radomir Cabala, Vera Pacakova, Zuzana Bosakova

Journal: Journal of Separation Science

Abstract This review follows up on Part 1, which focused on classification and evaluation of single drop and sorbent‐based microextraction techniques. Membrane‐ and homogenous phase‐based microextraction techniques are discussed and classified in Part 2. These techniques are more recent than those in Part 1 and considerable attention has been paid to their development. The new methodologies are more sensitive and, thanks to their...

Read More thumbnail image: Critical evaluation of microextraction pretreatment techniquesPart 2 Membranesupported and homogenous phase based techniques

Meldonium long‐term excretion period and pharmacokinetics in blood and urine of healthy athlete volunteers

Published: Nov 12, 2018

Author(s): Olivier Rabin, Vladimir Uiba, Yulia Miroshnikova, Maksim Zabelin, Aleksander Samoylov, Vladislav Karkischenko, Sergey Semyonov, Tatiana Astrelina, Sergey Razinkin

Journal: Drug Testing and Analysis

Abstract Meldonium is a metabolic drug whose inclusion in the 2016 List of Prohibited Substances and Methods followed the analysis of data collected under the 2015 World Anti‐Doping Agency Monitoring Program. In the early months of 2016, anti‐doping laboratories reported an unusually high number of cases in which urine samples contained high concentrations of meldonium. Consequently, the meldonium excretion period in healthy...

Read More thumbnail image: Meldonium longterm excretion period and pharmacokinetics in blood and urine of healthy athlete volunteers

Worldwide distribution of blood values in elite track and field athletes: Biomarkers of altered erythropoiesis

Published: Nov 12, 2018

Author(s): Neil Robinson, Jonas Saugy, Frédéric Schütz, Raphael Faiss, Norbert Baume, Sylvain Giraud, Martial Saugy

Journal: Drug Testing and Analysis

Abstract For the first time, blood samples were collected in all athletes participating in a major sporting event of the International Association of Athletics Federations (IAAF) (Athletics World Championships 2011, Daegu, Korea). All variables obtained from blood analyses were incorporated into the individual blood profiles of each athlete for the so‐called athlete biological passport (ABP). This unprecedented data collection...

Read More thumbnail image: Worldwide distribution of blood values in elite track and field athletes Biomarkers of altered erythropoiesis

Cetyl‐alcohol‐reinforced hollow fiber solid/liquid‐phase microextraction and HPLC–DAD analysis of ezetimibe and simvastatin in human plasma and urine

Published: Nov 12, 2018

Author(s): Nabil N. AL‐Hashimi, Rand O. Shahin, Aqeel N. AL‐Hashimi, Ajeal M. Al Ajeal, Lubna H. Tahtamouni, Chanbasha Basheer

Journal: Biomedical Chromatography

Abstract A new cetyl‐alcohol‐reinforced hollow fiber solid/liquid‐phase microextraction (CA–HF–SLPME) followed by high‐performance liquid chromatography–diode array detection (HPLC–DAD) method was developed for simultaneous determination of ezetimibe and simvastatin in human plasma and urine samples. To prepare the CA–HF–SLPME device, the cetyl‐alcohol was immobilized into the pores of a 2.5 cm hollow fiber micro‐tube and the lumen...

Read More thumbnail image: Cetylalcoholreinforced hollow fiber solidliquidphase microextraction and HPLCDAD analysis of ezetimibe and simvastatin in human plasma and urine

Recent advances in capillary electrophoresis‐mass spectrometry: Instrumentation, methodology and applications

Published: Nov 12, 2018

Author(s): Alexander Stolz, Kevin Jooß, Oliver Höcker, Jennifer Römer, Johannes Schlecht, Christian Neusüß

Journal: ELECTROPHORESIS

Abstract Capillary electrophoresis (CE) offers fast and high‐resolution separation of charged analytes from small injection volumes. Coupled to mass spectrometry (MS), it represents a powerful analytical technique providing (exact) mass information and enables molecular characterization based on fragmentation. Although hyphenation of CE and MS is not straightforward, much emphasis has been placed on enabling efficient ionization and...

Read More thumbnail image: Recent advances in capillary electrophoresismass spectrometry Instrumentation methodology and applications

Detection of non‐small cell lung cancer cells based on microfluidic polarization microscopic image analysis

Published: Nov 12, 2018

Author(s): Yanjuan Wang, Junsheng Wang, Jie Meng, Gege Ding, Zhi Shi, Ruoyu Wang, Xiaohui Zhang

Journal: ELECTROPHORESIS

Abstract In early diagnosis of lung cancer, a polarization microscopy is a powerful tool to obtain the optical information of biological tissues. In this paper, a new microfluidic polarization imaging and analysis method was proposed for the detection and classification of cancer‐associated fibroblasts and the two kinds of non‐small cell lung cancer cells, A549 and H322. A polarizing microscopy system was constructed based on a...

Read More thumbnail image: Detection of nonsmall cell lung cancer cells based on microfluidic polarization microscopic image analysis

Microfluidic device embedding electrodes for dielectrophoretic manipulation of cells‐A review

Published: Nov 12, 2018

Author(s): Jiafeng Yao, Guiping Zhu, Tong Zhao, Masahiro Takei

Journal: ELECTROPHORESIS

Abstract Microfluidic device embedding electrodes realizes cell manipulation with the help of dielectrophoresis. Cell manipulation is an important technology for cell sorting and cell population purification. Till now, the theory of dielectrophoresis has been greatly developed. Microfluidic devices with various arrangements of electrodes have been reported from the beginning of the single non‐uniform electric field to the later...

Read More thumbnail image: Microfluidic device embedding electrodes for dielectrophoretic manipulation of cellsA review

Evaporative characteristics of sessile nanofluid droplet on micro‐structured heated surface

Published: Nov 12, 2018

Author(s): Gui‐Ping Zhu, Kian‐Soo Ong, Karen Siew‐Ling Chong, Jia‐Feng Yao, Hu‐Lin Huang, Fei Duan

Journal: ELECTROPHORESIS

Abstract Micro‐structure patterned substrates attract our attention due to the special and programmable wettabilities. The interaction between the liquid and micro/nano structures gives rise to controllable spreading and thus evaporation. For exploration of the application versatility, the introduction of nanoparticles in liquid droplet results in interaction among particles, liquid and microstructures. In addition, temperature of...

Read More thumbnail image: Evaporative characteristics of sessile nanofluid droplet on microstructured heated surface
Page:   Prev 4 5 6 7 8 9 10 11 12 13 14 Next

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Most Viewed

Copyright Information

Interested in spectroscopy? Visit our sister site spectroscopyNOW.com

Copyright © 2018 John Wiley & Sons, Inc. All Rights Reserved