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Postmortem interval: Forensic proteomic pointers

Date: May 1, 2018

Author: Steve Down

A proteomics study of decaying bones has thrown up a number of proteins that might prove to be valuable markers of the skeletal postmortem interval as an aid to forensic scientists.

Read More thumbnail image: Postmortem interval Forensic proteomic pointers

Journal Highlight: Cell‐free DNA blood collection tubes are appropriate for clinical proteomics: A demonstration in colorectal cancer

Date: Apr 30, 2018

Author: separationsNOW

A proteomics study of colorectal cancer patients has shown that optimized blood collection tubes are appropriate for low‐abundant plasma protein analysis and can be used with confidence for clinical proteomics.

Read More thumbnail image: Journal Highlight Cellfree DNA blood collection tubes are appropriate for clinical proteomics A demonstration in colorectal cancer

Journal Highlight: Detection of trace amounts of citrinin in dried orange peel by using an optimized extraction method coupled with ultra‐performance liquid chromatography–tandem mass spectrometry

Date: Apr 23, 2018

Author: separationsNOW

A fast and sensitive method involving ultra‐performance liquid chromatography–tandem mass spectrometry has been introduced to detect the mycotoxin citrinin in dried orange peel.

Read More thumbnail image: Journal Highlight Detection of trace amounts of citrinin in dried orange peel by using an optimized extraction method coupled with ultraperformance liquid chromatographytandem mass spectrometry

Viral VOCs: Optimizing the extraction of VOCs from infected cells

Date: Apr 16, 2018

Author: Jon Evans

Researchers in the US have developed an optimized solid-phase microextraction method for extracting volatile organic compounds from cells infected with viruses, as a way of diagnosing viral diseases.

Read More thumbnail image: Viral VOCs Optimizing the extraction of VOCs from infected cells

Illuminating fingerprints: A novel fluorescence-based system for detecting proteins

Date: Apr 16, 2018

Author: Jon Evans

Indian scientists have developed a fluorescence-based system that can reveal a whole load of information about proteins separated by gel electrophoresis while they’re still embedded in the gel.

Read More thumbnail image: Illuminating fingerprints A novel fluorescence-based system for detecting proteins

Driving CE round the bend: Exploring biomolecule interactions with bent capillaries

Date: Apr 16, 2018

Author: Jon Evans

A team of Chinese and US scientists has found a bendy new way to make capillary electrophoresis more effective at analyzing the interaction between biomolecules.

Read More thumbnail image: Driving CE round the bend Exploring biomolecule interactions with bent capillaries

Journal Highlight: Simultaneous determination of glycol ethers and their acetates in cosmetics by GC–MS

Date: Apr 16, 2018

Author: separationsNOW

A GC/MS method has been developed for the simultaneous determination of ten kinds of toxic glycol ethers and their acetates in cosmetics, with method validation from different laboratories.

Read More thumbnail image: Journal Highlight Simultaneous determination of glycol ethers and their acetates in cosmetics by GCMS

Anton Checkov: Cause of death questioned

Date: Apr 15, 2018

Author: Steve Down

Proteome analysis of brown stains on archived personal items of Anton Checkov has yielded proteins related to Mycobacterium tuberculosis, confirming that he had tuberculosis at time of death, but another protein suggests that there may have been a different cause of death.

Read More thumbnail image: Anton Checkov Cause of death questioned

Thinking inside the box: A novel alternative to preparative chromatography

Date: Apr 9, 2018

Author: Jon Evans

Canadian researchers show that a box filled with ion-exchange particles offers a more efficient way to purify protein-based biopharmaceuticals than conventional preparative chromatography.

Read More thumbnail image: Thinking inside the box A novel alternative to preparative chromatography

Liquorice lessens alarming alkaloid levels

Date: Apr 9, 2018

Author: Ryan De Vooght-Johnson

The seeds of the tree Strychnos nux-vomica (‘Semen Strychni’), are used in traditional Chinese medicine, despite containing the poisonous alkaloids strychnine and brucine. Scientists from the Central South University (Changsha, China) used LC-MS to examine alkaloids from ‘Semen Strychni’ and compounds from liquorice, since it has been claimed that liquorice can reduce the toxicity of these seeds.

Read More thumbnail image: Liquorice lessens alarming alkaloid levels
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