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Clever chemometrics catches funny honey cheats

Date: Nov 1, 2017

Author: Ryan De Vooght-Johnson

Honey commands a variety of prices, depending in part on the source of the nectar from which it is derived, which may lead to fraudulent false labelling. Scientists from the Chinese Academy of Inspection and Quarantine in Beijing and Agilent Technologies (China) have devised a new method for detecting the source of honey samples, using GC-MS combined with chemometric methods.

Read More thumbnail image: Clever chemometrics catches funny honey cheats

Drink drug’s determination in hair described

Date: Nov 1, 2017

Author: Ryan De Vooght-Johnson

The anti-spasticity pharmaceutical baclofen is being investigated as a possible treatment for alcoholics, but compliance with the course of treatment can be a problem. Researchers from the Raymond Poincaré Hospital and Necker Hospital (both in Paris) have developed a new method of measuring baclofen in the hair of treated alcoholics, using LC/MS to determine how much of the drug has been taken.

Read More thumbnail image: Drink drugs determination in hair described

Journal Highlight: A robust protocol for the isolation of cellular proteins from Xanthomonas campestris to analyze the methionine effect in 2D-gel experiments

Date: Oct 30, 2017

Author: separationsNOW

A phenol extraction protocol developed for the purification of bacterial proteins that provides excellent 2D gel separation has been illustrated by examining the effects of methionine on the cellular proteome of Xanthomonas campestris.

Read More thumbnail image: Journal Highlight A robust protocol for the isolation of cellular proteins from Xanthomonas campestris to analyze the methionine effect in 2D-gel experiments

Journal Highlight: Tryptophan and cysteine oxidation products dominate in α-lactalbumin-derived peptides analyzed with LC–MSn

Date: Oct 23, 2017

Author: separationsNOW

The oxidation products of tryptophan and cysteine residues in α-lactalbumin, a major milk whey protein, have been identified, which will help to monitor the safety of protein-containing foods, including food supplements for sports nutrition.

Read More thumbnail image: Journal Highlight Tryptophan and cysteine oxidation products dominate in -lactalbumin-derived peptides analyzed with LCMSn

Journal Highlight: Probing skin physiology through the volatile footprint: Discriminating volatile emissions before and after acute barrier disruption

Date: Oct 23, 2017

Author: separationsNOW

Researchers in Ireland have used a small wearable housing integrating a solid-phase micro-extraction fiber, together with gas chromatography-mass spectrometry, to analyze the volatile organic compounds emitted by human skin.

Read More thumbnail image: Journal Highlight Probing skin physiology through the volatile footprint Discriminating volatile emissions before and after acute barrier disruption

Journal Highlight: Lipid profiling of parkin-mutant human skin fibroblasts

Date: Oct 23, 2017

Author: separationsNOW

Scientists in Italy used thin-layer chromatography to investigate possible lipid alterations associated with the lack of a protein called parkin, mutations of which are a major cause of early-onset Parkinson's disease, in skin primary fibroblasts.

Read More thumbnail image: Journal Highlight Lipid profiling of parkin-mutant human skin fibroblasts

Journal Highlight: A comparative proteomic analysis of blood serum for developmental stages in pigs

Date: Oct 23, 2017

Author: separationsNOW

Korean scientists have used two-dimensional gel electrophoresis to study how protein expression changes as pigs grow and develop over the first 150 days from birth.

Read More thumbnail image: Journal Highlight A comparative proteomic analysis of blood serum for developmental stages in pigs

More than the sum of its parts: Detecting endotoxins with SPE, CE and LIF

Date: Oct 16, 2017

Author: Jon Evans

A combination of solid-phase extraction, capillary electrophoresis and laser-induced fluorescence detection produces a sensitive and highly selective method for detecting bacterial endotoxins.

Read More thumbnail image: More than the sum of its parts Detecting endotoxins with SPE CE and LIF

A gap opens up: Analyzing protein binding with CE and surface plasmon resonance

Date: Oct 16, 2017

Author: Jon Evans

To analyze protein binding with capillary electrophoresis and surface plasmon resonance, Dutch scientists found they needed to scratch a gap into a gold sensor.

Read More thumbnail image: A gap opens up Analyzing protein binding with CE and surface plasmon resonance

ELISA meet NLISA: A novel immunosorbent assay with gel electrophoresis

Date: Oct 16, 2017

Author: Jon Evans

A novel form of immunosorbent assay utilizing gel electrophoresis is faster, more sensitive and less prone to false detections than existing versions, and could form the basis for quick and cheap medical diagnosis devices.

Read More thumbnail image: ELISA meet NLISA A novel immunosorbent assay with gel electrophoresis
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