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Foundations of Forensic Document Analysis: Theory and Practice

Date: Sep 18, 2015

Author: Michael J. Allen

Forensic document examination is a long established specialty and its practitioners have regularly been shown to have acquired skills that enable them to assist the judicial process.  This book, aimed primarily at students studying forensic science and document examination in particular, introduces all of the essential ideas that are to be found in the work of the forensic document examiner in a concise and straightforward way.  Each examination type is described not only in terms of its...

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Mass Spectra of Flavors and Fragrances of Natural and Synthetic Compounds, 3rd Edition

Date: Aug 31, 2015

Author: Luigi Mondello

Advanced Flavor and Fragrance Component Identification in Complex Mixtures Essential oils are mixtures consisting of monoterpene and sesquiterpene monocarbons, their oxygenated derivatives, and aliphatic oxygenated compounds. The difficulties that arise in he GC-MS peak identification of these complex samples is due to the fact that many terpense have identical mass spectra. This is a consequence of similiarities both in the initial molecule, or in the fragmentation patterns and rearrangements after...

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Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry

Date: Jul 17, 2015

Author: Steen Honore Hansen, Stig Pedersen-Bjergaard

Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry is the first student textbook on the separation science and mass spectrometry of pharmaceuticals present in biological fluids with an educational presentation of the principles, concepts and applications. It discusses the chemical structures and properties of low- and high-molecular drug substances; the different types of biological samples and fluids that are used; how to prepare the samples by extraction, and...

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Hydrogen Exchange Mass Spectrometry of Proteins

Date: Jul 3, 2015

Author: David Weis

Hydrogen exchange mass spectrometry is widely recognized for its ability to probe the structure and dynamics of proteins. The application of this technique is becoming widespread due to its versatility for providing structural information about challenging biological macromolecules such as antibodies, flexible proteins and glycoproteins. Although the technique has been around for 25 years, this is the first definitive book devoted entirely to the topic. Hydrogen Exchange Mass Spectrometry of Proteins:...

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Mass Spectrometry for the Analysis of Pesticide Residues and their Metabolites

Date: Jun 2, 2015

Author: Despina Tsipi, Helen Botitsi, Anastasios Economou

Provides an overview of the use of mass spectrometry (MS) for the analysis of pesticide residues and their metabolites. Presents state of the-art MS techniques for the identification of pesticides and their transformation products in food and environment Covers important advances in MS techniques including MS instrumentation and chromatographic separations (e.g. UPLC, HILIC, comprehensive GCxGC) and applications Illustrates the main sample preparation techniques (SPE, QuEChERS, microextraction) used in...

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Analyzing Biomolecular Interactions by Mass Spectrometry

Date: May 15, 2015

Author: Jeroen Kool, Wilfried M. A. Niessen

This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section...

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Pharmaceutical Amorphous Solid Dispersions

Date: May 13, 2015

Author: Ann Newman

Providing a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology – a leading platform to deliver poorly water soluble drugs, a major hurdle in today’s pharmaceutical industry. • Helps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems • Covers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property,...

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Mass Spectra of Designer Drugs 2015

Date: May 13, 2015

Author: Peter Rosner

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Biomarker Validation: Technological, Clinical and Commercial Aspects

Date: Apr 15, 2015

Author: Harald Seitz, Sarah Schumacher

Built on a decade of experience with novel molecular diagnostics, this practice-oriented guide shows how to cope with validation issues during all stages of biomarker development, from the first clinical studies to the eventual commercialization of a new diagnostic test.

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Biomedical Image Understanding: Methods and Applications

Date: Apr 3, 2015

Author: Joo-Hwee Lim, Sim-Heng Ong, Wei Xiong

A comprehensive guide to understanding and interpreting digital images in medical and functional applications Biomedical Image Understanding focuses on image understanding and semantic interpretation, with clear introductions to related concepts, in-depth theoretical analysis, and detailed descriptions of important biomedical applications. It covers image processing, image filtering, enhancement, de-noising, restoration, and reconstruction; image segmentation and feature extraction; registration;...

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