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HIV-1 and cocaine: Plasma proteome alterations

Date: Sep 15, 2015

Author: Steve Down

The effects of cocaine on the proteome of women infected with HIV-1 have been examined by scientists in Puerto Rico who found that the drug increased levels of apolipoprotein CIII, leading to a greater risk of stroke.

Read More thumbnail image: HIV-1 and cocaine Plasma proteome alterations

Folate and follicle fluid: Proteome analysis in women receiving IVF

Date: Sep 1, 2015

Author: Steve Down

Folic acid supplementation affects the proteome of follicular fluid in women on fertility treatment programmes, which may lead to the discovery of biomarkers for successful IVF or ICSI outcomes.

Read More thumbnail image: Folate and follicle fluid Proteome analysis in women receiving IVF

Journal Highlight: Proteomic analysis of cellular soluble proteins from human bronchial smooth muscle cells by combining nondenaturing micro 2DE and quantitative LC-MS/MS. 1. Preparation of more than 4000 native protein maps

Date: Aug 31, 2015

Author: separationsNOW

Soluble proteins of human bronchial smooth muscle cells were separated by nondenaturing micro 2DE and the proteins in 972 gel pieces were measured by LC-MS/MS to give 4323 native protein maps.

Read More thumbnail image: Journal Highlight Proteomic analysis of cellular soluble proteins from human bronchial smooth muscle cells by combining nondenaturing micro 2DE and quantitative LC-MSMS_ 1_ Preparation of more than 4000 native protein maps

Radiation therapy damage: Serum proteins affected

Date: Aug 15, 2015

Author: Steve Down

Radiation therapy for cancer patients affects the serum proteome, increasing levels of proteins associated with acute phase inflammation and reducing levels of lipoproteins and those involved in blood coagulation.

Read More thumbnail image: Radiation therapy damage Serum proteins affected

Journal Highlight: Proteomics beyond trypsin

Date: Aug 3, 2015

Author: separationsNOW

Some of the shortcomings of the nearly exclusive use of trypsin in proteomics are discussed and properties of other proteomics-appropriate proteases are reviewed, with examples of the increased coverage that can be achieved.

Read More thumbnail image: Journal Highlight Proteomics beyond trypsin

HIV antiretroviral therapy: Gender differences revealed by proteomics

Date: Aug 1, 2015

Author: Steve Down

The gender of HIV patients has a direct effect on the outcome of long-term antiretroviral therapy, favouring women, according to Chinese scientists who used proteomics to look at the proteins that were affected.

Read More thumbnail image: HIV antiretroviral therapy Gender differences revealed by proteomics

Poplar proteomics: Trees from distant sites compared

Date: Jul 15, 2015

Author: Steve Down

The proteome of poplar trees grown on grassland that had been irrigated for 40 years with starch wastewater from the potato industry reflected less abiotic stress than poplars grown in a forest, which suffered from phosphate ion deficiency.

Read More thumbnail image: Poplar proteomics Trees from distant sites compared

Iron age: Role in Bordetella pertusis growth

Date: Jul 2, 2015

Author: Steve Down

The role of iron in the life of Bordetella pertussis, the bacterium that causes whooping cough, has been examined by proteome analysis, revealing which proteins are affected by iron starvation.

Read More thumbnail image: Iron age Role in Bordetella pertusis growth

Journal Highlight: Proteomics analysis of malignant and benign prostate tissue by 2D DIGE/MS reveals new insights into proteins involved in prostate cancer

Date: Jun 29, 2015

Author: separationsNOW

Comparative proteomics analysis of prostate cancer and benign prostate hyperplasia tissues was carried out to clarify the proteins and regulatory pathways involved in the disease.

Read More thumbnail image: Journal Highlight Proteomics analysis of malignant and benign prostate tissue by 2D DIGEMS reveals new insights into proteins involved in prostate cancer

Protein pollution indicators: Livers of wild mice reflect environmental contamination

Date: Jun 17, 2015

Author: Steve Down

Spanish scientists have used proteomics techniques to measure protein changes in the liver of Mediterranean mice living in a national park, as a way to identify potential biomarkers of environmental pollution.

Read More thumbnail image: Protein pollution indicators Livers of wild mice reflect environmental contamination
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