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Milk whey glycoproteins: Interspecies comparison

Date: Apr 15, 2017

Author: Steve Down

A comprehensive examination of the glycoproteins in the milk whey from several mammals by Chinese researchers has identified more than 200 N-glycosylation sites, the majority of which have not been reported previously.

Read More thumbnail image: Milk whey glycoproteins Interspecies comparison

Journal Highlight: Sample clean-up strategies for electrospray ionization mass spectrometry applications in bottom-up proteomics: Trends from 2012–2016

Date: Apr 3, 2017

Author: separationsNOW

Research papers from 2012–2016 on strategies for removal of salts and surfactants prior to electrospray ionization MS analysis in bottom-up proteomics, mostly based on SPE and membrane-based FASP, have been reviewed.

Read More thumbnail image: Journal Highlight Sample clean-up strategies for electrospray ionization mass spectrometry applications in bottom-up proteomics Trends from 20122016

Forensic body fluids: Protein biomarkers

Date: Apr 2, 2017

Author: Steve Down

Biological stains such as urine, saliva and seminal fluid can be distinguished from each other using panels of unique protein biomarkers, offering a reliable way to assign the origin of a DNA profile in forensic cases, say researchers in the USA.

Read More thumbnail image: Forensic body fluids Protein biomarkers

Ant venom: Protein and peptide profiles

Date: Mar 16, 2017

Author: Steve Down

Peptides and proteins in the venom of the South American bullet ant have been compared following two extraction methods, with the ultimate aim of finding new drug and biopesticide candidates.

Read More thumbnail image: Ant venom Protein and peptide profiles

Journal Highlight: Genomics, transcriptomics and proteomics: enabling insights into social evolution and disease challenges for managed and wild bees

Date: Mar 6, 2017

Author: separationsNOW

Recent developments in honey bee and native bee research in the genomic era are discussed, covering progress in genome sequencing and functional annotation, enabled comparative genomics, social evolution and health.

Read More thumbnail image: Journal Highlight Genomics transcriptomics and proteomics enabling insights into social evolution and disease challenges for managed and wild bees

Saliva for disease biomarkers: Gender and acid stimulation effects

Date: Mar 1, 2017

Author: Steve Down

A more complete understanding of the effects of gender and acid simulation on the saliva proteome has been provided by scientists in China to help support the search for disease-specific biomarkers.

Read More thumbnail image: Saliva for disease biomarkers Gender and acid stimulation effects

Neutrophils and surgical trauma: Protein alterations

Date: Feb 15, 2017

Author: Steve Down

The activation of neutrophils following surgery has been studied by proteomic techniques to reveal some of the biochemical processes that are affected by trauma, offering therapeutic targets to treat post-operative complications.

Read More thumbnail image: Neutrophils and surgical trauma Protein alterations

Induced pluripotent stem cells: Proteomics test

Date: Feb 2, 2017

Author: Steve Down

Induced pluripotent human stem cells can be distinguished from non-pluripotent cells within minutes using a novel proteomics assay that targets 15 biomarker peptides originating from 4 particular transcription factors.

Read More thumbnail image: Induced pluripotent stem cells Proteomics test

Journal Highlight: Comparison of sample preparation techniques for large-scale proteomics

Date: Jan 30, 2017

Author: separationsNOW

The performances of several common sample preparation techniques for proteomic characterization of HeLa lysates have been compared, proteome sequence coverage increasing to 38% when combining all workflows.

Read More thumbnail image: Journal Highlight Comparison of sample preparation techniques for large-scale proteomics

Acute kidney injury: Biomarker protocol with labelled proteins

Date: Jan 15, 2017

Author: Steve Down

A novel method for accurately measuring multiple biomarkers of acute kidney injury that was developed in France uses isotope-labelled protein standards and can be rolled out to other diseases in different clinical scenarios.

Read More thumbnail image: Acute kidney injury Biomarker protocol with labelled proteins
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