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Iron age: Role in Bordetella pertusis growth

Date: Jul 2, 2015

Author: Steve Down

The role of iron in the life of Bordetella pertussis, the bacterium that causes whooping cough, has been examined by proteome analysis, revealing which proteins are affected by iron starvation.

Read More thumbnail image: Iron age Role in Bordetella pertusis growth

Journal Highlight: Proteomics analysis of malignant and benign prostate tissue by 2D DIGE/MS reveals new insights into proteins involved in prostate cancer

Date: Jun 29, 2015

Author: separationsNOW

Comparative proteomics analysis of prostate cancer and benign prostate hyperplasia tissues was carried out to clarify the proteins and regulatory pathways involved in the disease.

Read More thumbnail image: Journal Highlight Proteomics analysis of malignant and benign prostate tissue by 2D DIGEMS reveals new insights into proteins involved in prostate cancer

Protein pollution indicators: Livers of wild mice reflect environmental contamination

Date: Jun 17, 2015

Author: Steve Down

Spanish scientists have used proteomics techniques to measure protein changes in the liver of Mediterranean mice living in a national park, as a way to identify potential biomarkers of environmental pollution.

Read More thumbnail image: Protein pollution indicators Livers of wild mice reflect environmental contamination

Heart disease prediction: Urinary peptide signals

Date: Jun 1, 2015

Author: Steve Down

A panel of peptide biomarkers designed for differentiating between patients with or without coronary heart disease has now been used to predict coronary events in asymptomatic patients suffering from hypertension.

Read More thumbnail image: Heart disease prediction Urinary peptide signals

Journal Highlight: A sarabande of tropical fruit proteomics: Avocado, banana, and mango

Date: Jun 1, 2015

Author: separationsNOW

This review highlights the progress made in plant proteomics via the introduction of combinatorial peptide ligand libraries (CPLL) for detecting low-abundance species.

Read More thumbnail image: Journal Highlight A sarabande of tropical fruit proteomics Avocado banana and mango

Cereal allergens: Food processing effects revealed by proteomics

Date: May 15, 2015

Author: Steve Down

Processing wheat into couscous and barley into malt reduces the levels of many allergenic proteins, say Czech researchers, who showed that the iTRAQ mass spectrometric labelling system is a useful way to measure food allergens.

Read More thumbnail image: Cereal allergens Food processing effects revealed by proteomics

Journal Highlight: Clinical proteomics: Promises, challenges and limitations of affinity arrays

Date: May 4, 2015

Author: separationsNOW

The contribution that protein microarray formats could play towards proteome-based diagnostics is discussed and the obstacles are outlined, such as the current inability to produce complex sophisticated arrays.

Read More thumbnail image: Journal Highlight Clinical proteomics Promises challenges and limitations of affinity arrays

Genetically modified beans: Proteomics tells them apart

Date: May 1, 2015

Author: Steve Down

The proteomes of the leaves of genetically modified beans have been compared to their conventional counterparts, allowing a clear differentiation between the two forms of this important food crop.

Read More thumbnail image: Genetically modified beans Proteomics tells them apart

Thrombosis biomarkers: Proteins identify leukaemia patients at risk from asparaginase therapy

Date: Apr 15, 2015

Author: Steve Down

Proteomic analysis of the cerebrospinal fluid of children with acute lymphoblastic leukaemia under asparaginase therapy might be a way to identify those at risk from thrombosis, say US researchers.

Read More thumbnail image: Thrombosis biomarkers Proteins identify leukaemia patients at risk from asparaginase therapy

Salivary proteomics: Mammalian comparison

Date: Apr 4, 2015

Author: Steve Down

A comparison of the saliva proteomes of seven mammals from four evolutionary groups has revealed that most protein families are shared between species despite the high variability of individual proteins.

Read More thumbnail image: Salivary proteomics Mammalian comparison
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