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Thrombosis biomarkers: Proteins identify leukaemia patients at risk from asparaginase therapy

Date: Apr 15, 2015

Author: Steve Down

Proteomic analysis of the cerebrospinal fluid of children with acute lymphoblastic leukaemia under asparaginase therapy might be a way to identify those at risk from thrombosis, say US researchers.

Read More thumbnail image: Thrombosis biomarkers Proteins identify leukaemia patients at risk from asparaginase therapy

Salivary proteomics: Mammalian comparison

Date: Apr 4, 2015

Author: Steve Down

A comparison of the saliva proteomes of seven mammals from four evolutionary groups has revealed that most protein families are shared between species despite the high variability of individual proteins.

Read More thumbnail image: Salivary proteomics Mammalian comparison

Journal Highlight: Fourteen years of plant proteomics reflected in Proteomics: Moving from model species and 2DE-based approaches to orphan species and gel-free platforms

Date: Mar 30, 2015

Author: separationsNOW

Papers on plant proteomics published in the journal Proteomics have been reviewed in two sections covering experimental systems and methodology.

Read More thumbnail image: Journal Highlight Fourteen years of plant proteomics reflected in Proteomics Moving from model species and 2DE-based approaches to orphan species and gel-free platforms

Male infertility markers: Proteins influenced by reactive oxygen species

Date: Mar 15, 2015

Author: Steve Down

Proteins in infertile human sperm that are affected by low, medium and high excesses of reactive oxygen species have been identified, highlighting those that have reproductive functions.

Read More thumbnail image: Male infertility markers Proteins influenced by reactive oxygen species

Respiratory carbon nanotubes: Proteins secreted in lung fluid

Date: Mar 2, 2015

Author: Steve Down

Carbon nanotubes alter the proteome of the bronchoalveolar lavage fluid of mice, increasing the amounts of proteins associated with inflammation and immune response and pointing to the toxic response mechanism.

Read More thumbnail image: Respiratory carbon nanotubes Proteins secreted in lung fluid

Journal Highlight: Coupling enrichment methods with proteomics for understanding and treating disease

Date: Mar 2, 2015

Author: separationsNOW

The use of different proteomics-coupled enrichment techniques for aiding target and biomarker discovery has been reviewed to help understand the pathophysiology of various diseases.

Read More thumbnail image: Journal Highlight Coupling enrichment methods with proteomics for understanding and treating disease

Quinoa seed proteome: Non-model plant examined

Date: Feb 15, 2015

Author: Steve Down

A proteomic study of seeds of the emerging food quinoa has identified 352 proteins using a combination of three protein extraction procedures.

Read More thumbnail image: Quinoa seed proteome Non-model plant examined

Ancient adhesive: Proteomics reveals bovine origin of 3500-year-old Chinese glue

Date: Feb 4, 2015

Author: Steve Down

An adhesive scraped off a 3500-year-old Chinese artefact was made from cattle, say Chinese researchers, who used proteomics to prove its origins.

Read More thumbnail image: Ancient adhesive Proteomics reveals bovine origin of 3500-year-old Chinese glue

Journal Highlight: The human embryonic stem cell proteome revealed by multidimensional fractionation followed by tandem mass spectrometry

Date: Feb 1, 2015

Author: separationsNOW

An in-depth multidimensional fractionation followed by LC-MS/MS analysis of human embryonic stem cells has been carried out to elucidate expressed, phosphorylated, O-linked β-N-acetylglucosamine-modified and secreted proteins.

Read More thumbnail image: Journal Highlight The human embryonic stem cell proteome revealed by multidimensional fractionation followed by tandem mass spectrometry

Perflorooctane sulphonate toxicity: Proteomics study of liver cell damage

Date: Jan 15, 2015

Author: Steve Down

The effects of perfluorooctane sulphonate on human liver cells have been examined by proteomics techniques to help identify biomarkers for monitoring and contamination and expose the hepatotoxicity mechanisms.

Read More thumbnail image: Perflorooctane sulphonate toxicity Proteomics study of liver cell damage
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