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Influenza A proteins: Individual proteome variations

Date: Oct 15, 2017

Author: Steve Down

Scientists in the US have shown that the proteomes of normal human bronchial epithelial cells are unique for individual people and also respond to infection by the influenza A virus in different ways, findings which could be used to identify people more susceptible to the disease.

Read More thumbnail image: Influenza A proteins Individual proteome variations

Discover leading research in cannabis detection

Date: Oct 3, 2017

Author:

Cannabinoid research from an analytical viewpoint is rapidly developing as a more liberal approach to the medical, legal and social issues of the drug is adopted. Start reading our cannabinoid collection of papers here - free to access until the end of December.

Read More thumbnail image: Discover leading research in cannabis detection

Journal Highlight: A comparative analysis of human plasma and serum proteins by combining native PAGE, whole-gel slicing and quantitative LC-MS/MS: Utilizing native MS-electropherograms in proteomic analysis for discovering structure and interaction-correlated differences

Date: Oct 2, 2017

Author: separationsNOW

A new method combines native PAGE, whole-gel slicing and quantitative LC-MS/MS for the comparative analysis of proteins based not only on abundance, but also on their structures and interactions.

Read More thumbnail image: Journal Highlight A comparative analysis of human plasma and serum proteins by combining native PAGE whole-gel slicing and quantitative LC-MSMS Utilizing native MS-electropherograms in proteomic analysis for discovering structure and interaction-correlated differences

SCUBA diver proteome: Decompression stress vs. decompression sickness

Date: Oct 1, 2017

Author: Steve Down

In a follow-up study of the effects of decompression sickness on the proteome of rats, an international team of scientists has examined the effects of decompression stress on SCUBA divers in the absence of decompression sickness.

Read More thumbnail image: SCUBA diver proteome Decompression stress vs_ decompression sickness

Dialysis membranes: Adsorbed proteins

Date: Sep 15, 2017

Author: Steve Down

The effects of protein adsorption on two types of hemodialysis membrane have been studied by Chinese scientists to identify the unwanted biochemical reactions that occur in an effort to design more efficient membrane materials.

Read More thumbnail image: Dialysis membranes Adsorbed proteins

Journal Highlight: In-gel and OFFGEL-based proteomic approach for authentication of meat species from minced meat and meat products

Date: Sep 4, 2017

Author: separationsNOW

In-gel 2D gel electrophoresis and an OFFGEL-based proteomic method followed by the MALDI-TOF MS analysis of proteins have been used to authenticate raw and cooked water buffalo, sheep and goat meat and their mixes.

Read More thumbnail image: Journal Highlight In-gel and OFFGEL-based proteomic approach for authentication of meat species from minced meat and meat products

Dominant or submissive: Proteomic clues to behavioural disorders

Date: Aug 15, 2017

Author: Steve Down

The expression of many proteins in the hippocampi of mice are modified by dominant and submissive behaviour, say scientists in Israel in the first study of its kind which will help to decode the molecular mechanisms of psychiatric disorders and lead to therapeutic solutions.

Read More thumbnail image: Dominant or submissive Proteomic clues to behavioural disorders

Extended human proteome: Multishot procedure for single cell types

Date: Aug 1, 2017

Author: Steve Down

A novel strategy for deriving comprehensive human proteomes that relies on the offline HPLC separation of multiple injections of protein digests followed by fast scanning tandem mass spectrometry has identified more than 14,000 protein isoforms from a single human cell line.

Read More thumbnail image: Extended human proteome Multishot procedure for single cell types

Journal Highlight: Microproteomics with microfluidic-based cell sorting: Application to 1000 and 100 immune cells

Date: Jul 31, 2017

Author: separationsNOW

A microproteomics workflow for limited numbers of immune cells using non-damaging, microfluidic chip-based cell sorting and MS-based proteomics gave reasonable proteome coverage for 100 sorted cells and comprehensive data from 1000 sorted cells.

Read More thumbnail image: Journal Highlight Microproteomics with microfluidic-based cell sorting Application to 1000 and 100 immune cells

Extended beer proteome: Allergenic gluten proteins

Date: Jul 15, 2017

Author: Steve Down

The most extensive proteome of lager beer to date has been been derived by scientists in the Czech Republic who made a special effort to identify gluten proteins which might be allergenic.

Read More thumbnail image: Extended beer proteome Allergenic gluten proteins
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