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Mass Spectrometry in Drug Metabolism and Pharmacokinetics

Date: Jan 16, 2009

Author: Ragu Ramanathan

This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from the pharmaceutical industry, this book begins with a review of current mass spectrometry techniques and applications, followed by discussions of various methods for using MS in drug metabolism studies and pharmacokinetics. Highlighting the critical importance of ADME studies for understanding how a drug is absorbed, distributed, metabolized, and excreted by the body,...

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Introduction to Proteomics

Date: Nov 7, 2008

Author: Agnieszka Kraj, Jerzy Silberring

Introduction to Proteomics is written by seasoned researchers with years of practical experience. In addition to comprehensive discussions of the basic concepts, techniques, and applications of the subject, the text also includes an extensive glossary and a chapter containing laboratory exercises and protocols. While mass spectrometry is central to proteomics, the book discusses all of the analytical techniques a student is likely to need when faced with real-world problems, such as sample preparation,...

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Preclinical Development Handbook: ADME and Biopharmaceutical Properties

Date: Apr 29, 2008

Author: Shayne Cox Gad

A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for...

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Preclinical Development Handbook: Toxicology

Date: Apr 29, 2008

Author: Shayne Cox Gad

A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use resource discusses all the issues that need consideration and provides detailed instructions for current...

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Multidimensional Liquid Chromatography: Theory and Applications in Industrial Chemistry and the Life Sciences

Date: Apr 22, 2008

Author: Steven A. Cohen, Mark R. Schure

Multidimensional Liquid Chromatography (MDLC) is a very powerful separation technique for analyzing exceptionally complex samples in one step. This authoritative reference presents a number of recent contributions that help define the current art and science of MDLC. Topics covered include instrumentation, theory, methods development, and applications of MDLC in the life sciences and in industrial chemistry. With the information to help you perform very difficult separations of complex samples, this...

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Trace Quantitative Analysis by Mass Spectrometry

Date: Apr 18, 2008

Author: Robert K. Boyd, Cecilia Basic, Robert A. Bethem

This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry: Covers all aspects of the use of mass spectrometry for quantitation purposes Written in textbook style to facilitate understanding...

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Microsystem Engineering of Lab-on-a-Chip Devices

Date: Apr 16, 2008

Author: Oliver Geschke, Henning Klank, Pieter Telleman

Edited by an interdisciplinary team of scientists at one of the leading centers for microsystem research, this second edition retains the proven structure of its predecessor, enlarged by around 10%. Focusing on analytical applications mainly in life sciences, this is an invaluable companion for fast and automated analytical procedures, providing a concise practical approach to microtechnology.

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Hyphenated Techniques in Grape and Wine Chemistry

Date: Apr 11, 2008

Author: Riccardo Flamini

This book presents the modern applications of hyphenated techniques in the analysis and study of the chemistry of grape, wine, and grape-derivative products. It explains the different applications and techniques used in the laboratory, such as liquid- and gas-phase chromatography, mass spectrometry, and capillary electrophoresis, and describes the methods developed using instrumentation with high performance and reliability. Additionally, the book covers the principal applications of...

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Kirk-Othmer Separation Technology, 2 Volume Set, 2nd Edition

Date: Mar 14, 2008

Author: Wiley

This two-volume set delivers over seventy carefully selected articles on separation technology from the Kirk-Othmer Encyclopedia of Chemical Technology. Presenting readers with the principles of separation processes, process design, equipment, operation, and applications, it features content that has been expanded upon, updated, and modernized since publication of the first edition. Covering a wealth of critical topics, the articles have been arranged alphabetically for ease of use and focus on both...

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Biological Applications of Microfluidics

Date: Mar 7, 2008

Author: Frank A. Gomez

Microfluidics-today's applications and tomorrow's potential Microfluidics has facilitated major biochemical application advancements in point-of-care diagnostics, bioterrorism detection, and drug discovery. There are numerous potential applications in biotechnology, pharmaceuticals, the life sciences, defense, public health, and agriculture. Microfluidic lab-on-a-chip (LOC) technologies represent a revolution in laboratory experimentation, bringing the benefits of miniaturization, integration, and...

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