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Computational and Statistical Methods for Protein Quantification by Mass Spectrometry

Date: Jan 28, 2013

Author: Ingvar Eidhammer, Harald Barsnes, Geir Egil Eide, Lennart Martens

The definitive introduction to data analysis in quantitative proteomics This book provides all the necessary knowledge about mass spectrometry based proteomics methods and computational and statistical approaches to pursue the planning, design and analysis of quantitative proteomics experiments. The author’s carefully constructed approach allows readers to easily make the transition into the field of quantitative proteomics. Through detailed descriptions of wet-lab methods, computational approaches...

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International Tables for Crystallography, Volume F, 2nd Edition, Crystallography of Biological Macromolecules

Date: Jan 27, 2012

Author: Eddy Arnold, Daniel M. Himmel, Michael G. Rossmann

International Tables for Crystallography Volume F is an expert guide to macromolecular crystallography for the structural biologist. It was commissioned by the International Union of Crystallography in recognition of the extraordinary contributions that knowledge of macromolecular structure has made, and will make, to the analysis of biological systems, from enzyme catalysis to the workings of a whole cell. The volume covers all stages of a crystallographic analysis from the preparation of recombinant...

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Forensic Chemistry Handbook

Date: Jan 3, 2012

Author: Lawrence Kobilinsky

A concise, robust introduction to the various topics covered by the discipline of forensic chemistry The Forensic Chemistry Handbook focuses on topics in each of the major chemistry-related areas of forensic science. With chapter authors that span the forensic chemistry field, this book exposes readers to the state of the art on subjects such as serology (including blood, semen, and saliva), DNA/molecular biology, explosives and ballistics, toxicology, pharmacology, instrumental analysis, arson...

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Chemical Analysis of Antibiotic Residues in Food

Date: Dec 27, 2011

Author: Jian Wang, James D. MacNeil, Jack F. Kay

An insightful exploration of the key aspects concerning the chemical analysis of antibiotic residues in food The presence of excess residues from frequent antibiotic use in animals is not only illegal, but can pose serious health risks by contaminating products for human consumption such as meat and milk. Chemical Analysis of Antibiotic Residues in Food is a single-source reference for readers interested in the development of analytical methods for analyzing antibiotic residues in food. It covers themes...

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Protein and Peptide Mass Spectrometry in Drug Discovery

Date: Dec 23, 2011

Author: Michael L. Gross, Guodong Chen, Birendra Pramanik

The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing together the work of experts in academia and industry, Protein and Peptide Mass Spectrometry in Drug Discovery...

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Proteomics of Biological Systems: Protein Phosphorylation Using Mass Spectrometry Techniques

Date: Dec 16, 2011

Author: Bryan M. Ham

Phosphorylation is the addition of a phosphate (PO4) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine whether or not a protein has been correctly modified by the addition of a phosphate group. It also provides a combination of detailed, step-by-step methodology for phosphoproteomic sample preparation, mass...

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Mathematical Methods for Physical and Analytical Chemistry

Date: Nov 15, 2011

Author: David Z. Goodson

Mathematical Methods for Physical and Analytical Chemistry presents mathematical and statistical methods to students of chemistry at the intermediate, post-calculus level. The content includes a review of general calculus; a review of numerical techniques often omitted from calculus courses, such as cubic splines and Newton’s method; a detailed treatment of statistical methods for experimental data analysis; complex numbers; extrapolation; linear algebra; and differential equations. With...

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Organic Spectroscopy Workbook

Date: Sep 2, 2011

Author: Tom Forrest, Jean-Pierre Rabine, Michel Rouillard

Spectroscopy is used in physical and analytical chemistry for the identification of substances through the spectrum emitted from or absorbed by them. The derivation of structural information from spectroscopic data is now an integral part of many courses in chemistry and related subjects at most universities. This workbook: Features exercises to help develop the student's understanding of how structures are determined from spectra and to promote the student's own interpretation of different spectra....

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Comprehensive Chromatography in Combination with Mass Spectrometry

Date: Aug 26, 2011

Author: Luigi Mondello

This book provides a detailed description of various multidimensional chromatographic separation techniques. The editor first provides an introduction to the area and then dives right into the various complex separation techniques. While still not used routinely comprehensive chromatography techniques will help acquaint the readers with the fundamentals and possible benefits of multi-dimensional separations coupled with mass spectrometry. The topics include a wide range of material that will appease all...

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Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites, 4th Edition

Date: Aug 24, 2011

Author: Hans H. Maurer, Karl Pfleger, Armin A. Weber

The world's most comprehensive reference for forensic toxicologists is keeping pace with recent developments in clinical toxicology in its new release: Another 800 new spectra have been added to this gold standard, including novel designer drugs and a broad range of AIDS therapeutics, for a total of 8,650 clinically relevant substances, including 5,200 metabolites. The print edition contains a comprehensive listing of all compounds in order of molecular mass, showing a reference mass spectrum as well as...

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