New Nano LC System with ProFlow Technology Offers Advanced Low-flow Performance

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  • Published: Jan 27, 2016
  • Source: Thermo Fisher Scientific
  • Channels: Proteomics & Genomics / HPLC / Proteomics / Base Peak
thumbnail image: New Nano LC System with ProFlow Technology Offers Advanced Low-flow Performance

The Thermo Scientific UltiMate 3000 RSLCnano with ProFlow technology provides high-quality analyte identification and quantitation

GHENT, Belgium. January 27, 2016.

Scientists performing nano liquid chromatography/mass spectrometry (LC-MS) analyses who seek accurate quantitation and analyte identification can now use a system designed to deliver higher retention time precision and ease of use.

The latest version of the Thermo Scientific UltiMate 3000 RSLCnano UHPLC system combines higher nano LC performance with versatility and ease-of-use. New ProFlow technology increases retention time precision, resulting in high-quality data with accurate quantitation. Additionally, the system offers reduced start-up time and simplified system operation so that researchers can focus more time on data acquisition and analysis.

“Life scientists are pushing research boundaries, but they also rely on nano flow technology to enable more productive and efficient workflows,” said Remco Swart, Ph.D., director, LC-MS technologies, Thermo Fisher. “Our new nano UHPLC system combines the precision of ProFlow technology with ease of operation so that researchers can focus less on the technology and more on their work.”

The UltiMate 3000 RSLCnano offers a wide flow range (nano-to-micro flow rates) in UHPLC mode as well as an additional micro-to-analytical flow ternary gradient pump for increased versatility. As a result, almost any low-flow workflow can benefit from this system. Dedicated kits are available for many standard and advanced (e.g. two-dimensional) workflows. All connections use Thermo Scientific nanoViper fingertight fittings to ensure rapid and easy set-up and virtually zero-dead-volume connectivity. Additionally, dedicated software is available to integrate the system with Thermo Scientific mass spectrometers.

“ProFlow technology allows long-term nano LC-MS operation with less maintenance and the highest performance,” said Mark Larance, Ph.D., University of Dundee in Scotland, after testing the new technology.

The UltiMate 3000 RSLCnano HPLC system will be exhibited in booth 10 at the HTC 14 - 14th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology in Ghent, Belgium. The event takes place Jan. 27-29. Dr. Swart will introduce the new features of the system in a seminar entitled ”New Nano LC Performance Levels for Proteomics Workflows,” which takes place on Jan. 28 from 1:30-2:15 p.m.

More information on the UltiMate 3000 RSLCnano can be found at

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. is the world leader in serving science, with revenues of $17 billion and approximately 50,000 employees in 50 countries. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services – we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive support. For more information, please visit

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