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Pereskia bleo: A prickly source of antioxidants?

Date: Jan 1, 2016

Author: Ryan De Vooght-Johnson

Finding the compounds responsible for antioxidant activity is an important goal in herbal medicine analysis. Researchers have now developed an affordable way of doing this, which will enable developing countries to conduct the analysis.

Read More thumbnail image: Pereskia bleo A prickly source of antioxidants

Chasing the Chinese chastetree: Chemical fingerprint of a traditional herbal remedy

Date: Dec 14, 2015

Author: Ryan De Vooght-Johnson

A simple method for chemical fingerprint analysis of traditional Chinese medicines, using high-performance liquid chromatography with diode array detection, is described in a new study. The method was applied to Chinese chastetree seeds, establishing the first quality control standards for this herbal medicine.

Read More thumbnail image: Chasing the Chinese chastetree Chemical fingerprint of a traditional herbal remedy

Journal Highlight: Quantitative and qualitative determination of LiuweiDihuang preparations by UHPLC in dual-wavelength fingerprinting mode and random forest

Date: Dec 7, 2015

Author: separationsNOW

UHPLC with dual-wavelength detection was used to determine 11 constituents in LiuweiDihuang preparations, using a random forest technique on the spectrometric fingerprint data to distinguish four dosage forms.

Read More thumbnail image: Journal Highlight Quantitative and qualitative determination of LiuweiDihuang preparations by UHPLC in dual-wavelength fingerprinting mode and random forest

Healing powers of Chinese walnut

Date: Dec 1, 2015

Author: Ryan De Vooght-Johnson

Researchers describe a four-step approach to identify the active compounds in medicinal Chinese walnut, providing a blueprint for the systematic analysis of plant chemicals.

Read More thumbnail image: Healing powers of Chinese walnut

Journal Highlight: A novel four-step approach for systematic identification of naphthoquinones in Juglans cathayensis Dode using various scan functions of LC-tandem MS along with data mining strategies

Date: Nov 9, 2015

Author: separationsNOW

An efficient four-step approach has been developed for the systematic discovery and identification of naphthoquinones in Juglans cathayensis using various scan functions in LC/MS of with data mining strategies.

Read More thumbnail image: Journal Highlight A novel four-step approach for systematic identification of naphthoquinones in Juglans cathayensis Dode using various scan functions of LC-tandem MS along with data mining strategies

Frankincense: from biblical incense to anti-inflammatory

Date: Nov 1, 2015

Author: Ryan De Vooght-Johnson

Frankincense has been used as a traditional medicine for thousands of years, and its anti-inflammatory properties are now gathering interest in the pharmaceutical industry. In a new study, scientists describe a way of identifying the type of frankincense and evaluating its quality, which could be applied to other traditional medicines.

Read More thumbnail image: Frankincense from biblical incense to anti-inflammatory

Journal Highlight: Fingerprint analysis, multi-component quantitation, and antioxidant activity for the quality evaluation of Salvia miltiorrhiza var. alba by HPLC and chemometrics

Date: Oct 26, 2015

Author: separationsNOW

Chinese scientists have used liquid chromatography and various multivariate statistical techniques to identify the constituents of the medicial herb Salvia miltiorrhiza that are responsible for its antioxidant activity.

Read More thumbnail image: Journal Highlight Fingerprint analysis multi-component quantitation and antioxidant activity for the quality evaluation of Salvia miltiorrhiza var_ alba by HPLC and chemometrics

Proteins in parallel: New tool to compare protein expression could accelerate research

Date: Oct 12, 2015

Author: Ryan De Vooght-Johnson

Usually only a small percentage of proteins can be compared across samples in LC–MS/MS. A new software package, called MZDASoft, can integrate data from multiple samples, allowing clinical researchers to compare samples from many different patients.

Read More thumbnail image: Proteins in parallel New tool to compare protein expression could accelerate research

Bioinformatics tool rapidly verifies prostate cancer biomarkers

Date: Oct 1, 2015

Author: Ryan De Vooght-Johnson

Mass spectrometry is widely used to discover candidate biomarkers from complex samples of proteins. Yet, owing to sensitivity limitations, many biomarkers cannot be detected by standard mass spectrometers. Surface-activated chemical ionisation combined with an electrospray ionisation source can overcome some of these limitations.

Read More thumbnail image: Bioinformatics tool rapidly verifies prostate cancer biomarkers

Journal Highlight: Cluster analysis of commercial samples of Bauhinia spp. using HPLC-UV/PDA and MCR-ALS/PCA without peak alignment procedure

Date: Sep 21, 2015

Author: separationsNOW

Using cluster analysis on HPLC data, scientists from Australia and Brazil have been able to identify authentic samples of a Brazilian medicinal plant used to treat hypoglycemia and diabetes.

Read More thumbnail image: Journal Highlight Cluster analysis of commercial samples of Bauhinia spp_ using HPLC-UVPDA and MCR-ALSPCA without peak alignment procedure
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