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Journal Highlight: Variations in chemical fingerprints and major flavonoid contents from the leaves of thirty-one accessions of Hibiscus sabdariffa L.

Date: Jul 11, 2016

Author: separationsNOW

Similarity analysis and principal component analysis of HPLC data have been used to differentiate the 31 accessions of H. sabdariffa L.

Read More thumbnail image: Journal Highlight Variations in chemical fingerprints and major flavonoid contents from the leaves of thirty-one accessions of Hibiscus sabdariffa L_

Vendor Column: Advantages of a Scalable Chromatography Data System

Date: Jul 10, 2016

Author: Chris Stumpf

In this second article in the latest series, Waters Corporation's Chris Stumpf continues the discussion regarding chromatography data systems with respect to its rationlization and scalability within a corporation.

Read More thumbnail image: Vendor Column Advantages of a Scalable Chromatography Data System

Blind wine testing: Anthocyanin database enables identification in the laboratory

Date: Jul 1, 2016

Author: Ryan De Vooght-Johnson

See, sniff, sip, swirl. That's how wine connoisseurs are schooled to judge a prize-winning wine, but researchers envisage more scientific criteria. Published in Rapid Communications in Mass Spectrometry, scientists from China and New Zealand worked together to devise a method and complementary database that enable the identification of a vast array of anthocyanins not possible hitherto.

Read More thumbnail image: Blind wine testing Anthocyanin database enables identification in the laboratory

Rational drug design: structure dictates function in amide derivatives

Date: Jun 15, 2016

Author: Ryan De Vooght-Johnson

Amide derivatives can be anti-bacterials, insecticides, painkillers and antidepressants, depending on the interactions they form in the body. This study investigated the influence of their structure on these interactions using a range of multivariate methods, including principal component analysis.

Read More thumbnail image: Rational drug design structure dictates function in amide derivatives

Journal Highlight: Untargeted metabolic profiling of winery-derived biomass waste degradation by Aspergillus niger

Date: Jun 6, 2016

Author: separationsNOW

GC/MS analysis with covariance-inverse multivariate statistics were used to classify the most significant metabolites produced by the Aspergillus niger-mediated solid state fermentation of winery biomass waste of Vitis vinifera var. Shiraz.

Read More thumbnail image: Journal Highlight Untargeted metabolic profiling of winery-derived biomass waste degradation by Aspergillus niger

The rise and rise of bioactive proteins

Date: Jun 1, 2016

Author: Ryan De Vooght-Johnson

Recent advances in mass spectrometry have led to a surge in the search for so-called ‘bioactive proteins’: small proteins that can improve health. A surprising and underused source of these proteins is blood from meat production, of which 70% is currently wasted. This study found over 900 different peptides in just one sample.

Read More thumbnail image: The rise and rise of bioactive proteins

The metabolome of the bellyache bush

Date: May 15, 2016

Author: Ryan De Vooght-Johnson

Metabolites are small molecules that define species, yet there is still no efficient and reproducible way of analysing them. A new paper in the Journal of Separation Science might provide such a method: a sequential strategy for extracting and separating metabolites, applied to the Brazilian bellyache bush.

Read More thumbnail image: The metabolome of the bellyache bush

Journal Highlight: Oxidative stress and antioxidative systems: recipes for successful data collection and interpretation

Date: May 9, 2016

Author: separationsNOW

A critical overview is given of currently popular methodologies for generating oxidative stress in plants, measuring ROS and major antioxidant metabolites, and assaying antioxidative enzymes and marker transcripts for oxidative stress.

Read More thumbnail image: Journal Highlight Oxidative stress and antioxidative systems recipes for successful data collection and interpretation

The hidden chemicals in so-called ‘herbal’ diet pills

Date: May 1, 2016

Author: Ryan De Vooght-Johnson

Following numerous diet pill safety scandals, herbal medicines are becoming increasingly popular in the fight against the flab. In a new study from Belgium, scientists used chemical fingerprinting to analyse supposedly herbal diet pills – the first time fingerprinting has been used to evaluate the safety of illegal slimming aids.

Read More thumbnail image: The hidden chemicals in so-called herbal diet pills

A bittersweet family of plants

Date: Apr 14, 2016

Author: Ryan De Vooght-Johnson

The Gentian family of plants occur worldwide, especially in temperate areas. Despite their notoriously bitter taste, they can be effective at treating digestive problems. A study from China uses a novel combination of approaches for metabolic profiling of these plants, which may help to more accurately differentiate between species.

Read More thumbnail image: A bittersweet family of plants
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