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Another pair of eyes: improved ability to measure consistency of ophthalmic drug dosages

Date: Aug 17, 2016

Author: Ryan De Vooght-Johnson

Measuring the error of your novel analytical test one-variable-at-a-time is painstakingly slow, not to mention the huge amounts of data generated. In response, researchers from the University of La Laguna in Tenerife set out to devise a cheap and accessible test capable of measuring the conformity of triamcinolone acetonide within eye hydrogels using accessible technology and new-generation data crunching.

Read More thumbnail image: Another pair of eyes improved ability to measure consistency of ophthalmic drug dosages

Vendor Column: Two approaches to multi-vendor instrument support when standardizing your CDS Operations

Date: Aug 16, 2016

Author: Chris Stumpf

The cost of training and maintaining multiple Chromatography Data Systems are driving many organizations to standardize on a single chromatography data platform. In this first article in a brand new series, Waters Corporation's Chris Stumpf discusses things to think about when standardizing your chromatography data system (CDS) operations.

Read More thumbnail image: Vendor Column Two approaches to multi-vendor instrument support when standardizing your CDS Operations

Journal Highlight: Investigating the roles of dissolved organic matter on arsenic mobilization and speciation in environmental water

Date: Aug 8, 2016

Author: separationsNOW

Water from the three most heavily As-contaminated rivers in China was studied by SEC, ICPMS and 3D excitation-emission matrix fluorescence spectroscopy coupled with parallel factor analysis (PARAFAC) to clarify the role of dissolved organic matter in As removal.

Read More thumbnail image: Journal Highlight Investigating the roles of dissolved organic matter on arsenic mobilization and speciation in environmental water

Not a load of rhubarb: Study finds 16 chemicals that emerge from processing rhubarb

Date: Aug 1, 2016

Author: Ryan De Vooght-Johnson

Chinese physicians of bygone generations prescribed natural remedies for a multitude of ailments and maladies. Today, practitioners of Traditional Chinese Medicine are retracing their steps with modern analytical techniques in an attempt to elucidate the active components behind their therapeutic activity.

Read More thumbnail image: Not a load of rhubarb Study finds 16 chemicals that emerge from processing rhubarb

Oil spoils: saturated fatty acids improve the frying quality of olive oil

Date: Jul 14, 2016

Author: Ryan De Vooght-Johnson

Toxic products are created from the repeated use of cooking oils. In response, scientists from Universities of Sfax, Tunisa, and Pisa, Italy, worked together to modify the fatty acid component of refined palm oil, with the aim of improving its thermostability.

Read More thumbnail image: Oil spoils saturated fatty acids improve the frying quality of olive oil

Journal Highlight: Variations in chemical fingerprints and major flavonoid contents from the leaves of thirty-one accessions of Hibiscus sabdariffa L.

Date: Jul 11, 2016

Author: separationsNOW

Similarity analysis and principal component analysis of HPLC data have been used to differentiate the 31 accessions of H. sabdariffa L.

Read More thumbnail image: Journal Highlight Variations in chemical fingerprints and major flavonoid contents from the leaves of thirty-one accessions of Hibiscus sabdariffa L_

Vendor Column: Advantages of a Scalable Chromatography Data System

Date: Jul 10, 2016

Author: Chris Stumpf

In this second article in the latest series, Waters Corporation's Chris Stumpf continues the discussion regarding chromatography data systems with respect to its rationlization and scalability within a corporation.

Read More thumbnail image: Vendor Column Advantages of a Scalable Chromatography Data System

Blind wine testing: Anthocyanin database enables identification in the laboratory

Date: Jul 1, 2016

Author: Ryan De Vooght-Johnson

See, sniff, sip, swirl. That's how wine connoisseurs are schooled to judge a prize-winning wine, but researchers envisage more scientific criteria. Published in Rapid Communications in Mass Spectrometry, scientists from China and New Zealand worked together to devise a method and complementary database that enable the identification of a vast array of anthocyanins not possible hitherto.

Read More thumbnail image: Blind wine testing Anthocyanin database enables identification in the laboratory

Rational drug design: structure dictates function in amide derivatives

Date: Jun 15, 2016

Author: Ryan De Vooght-Johnson

Amide derivatives can be anti-bacterials, insecticides, painkillers and antidepressants, depending on the interactions they form in the body. This study investigated the influence of their structure on these interactions using a range of multivariate methods, including principal component analysis.

Read More thumbnail image: Rational drug design structure dictates function in amide derivatives

Journal Highlight: Untargeted metabolic profiling of winery-derived biomass waste degradation by Aspergillus niger

Date: Jun 6, 2016

Author: separationsNOW

GC/MS analysis with covariance-inverse multivariate statistics were used to classify the most significant metabolites produced by the Aspergillus niger-mediated solid state fermentation of winery biomass waste of Vitis vinifera var. Shiraz.

Read More thumbnail image: Journal Highlight Untargeted metabolic profiling of winery-derived biomass waste degradation by Aspergillus niger
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