Lab Informatics / Ezine

Skip to Navigation

Ezine RSS Feed

rss

Filter Ezines

Browse By Ezines

Filter by Supplier

Browse By Supplier

Journal Highlight: Fast and simple discriminative analysis of anthocyanins-containing berries using LC/MS spectral data

Date: Sep 11, 2017

Author: separationsNOW

An alternative approach for the quality assessment and discrimination of anthocyanin-containing berries has been developed using mass spectral data acquired in a short analytical time rather than UV or MS chromatograms.

Read More thumbnail image: Journal Highlight Fast and simple discriminative analysis of anthocyanins-containing berries using LCMS spectral data

MS muddle made manageable by mulitplierz software

Date: Sep 6, 2017

Author: Ryan De Vooght-Johnson

The diversity of current mass spectrometry methods and software tools has led to multiple arrays of data that are not readily comparable. Researchers from Harvard Medical School and the Dana-Farber Cancer Institute in Boston have reported on the latest version of their multiplierz software, which aims to provide a common platform for mass spectrometry proteomic data.

Read More thumbnail image: MS muddle made manageable by mulitplierz software

No standards involved, but are all problems solved?

Date: Aug 15, 2017

Author: Ryan De Vooght-Johnson

Modern analytical techniques, such as HRMS (high-resolution mass spectrometry), enable the simultaneous detection of a large number of compounds, but normally rely on analytical standards of all the compounds being available, which may not be the case. Researchers from the Zurich Official Food Control Authority have developed an LC-HRMS method that identifies compounds without the use of standards, demonstrating its efficiency by identifying veterinary compounds spiked into meat and fish extracts.

Read More thumbnail image: No standards involved but are all problems solved

Journal Highlight: Untargeted metabolomic profiling of seminal plasma in nonobstructive azoospermia men: A noninvasive detection of spermatogenesis

Date: Aug 8, 2017

Author: separationsNOW

Untargeted metabolomic profiling of the seminal plasma in men with nonobstructive azoospermia was studied by GC/MS and advance chemometrics, leading to 36 potential biomarkers of the condition.

Read More thumbnail image: Journal Highlight Untargeted metabolomic profiling of seminal plasma in nonobstructive azoospermia men A noninvasive detection of spermatogenesis

Hydrophilic interactions change along with volume fractions

Date: Aug 1, 2017

Author: Ryan De Vooght-Johnson

Hydrophilic interaction liquid chromatography (HILIC) is a relatively new method, so theoretical work on the relationships between its parameters is not as extensive as with older techniques. Scientists from the University of Belgrade looked at the association between peak retention and mobile phase composition for HILIC on the antipsychotic drug olanzapine and its impurities using various theoretical models.

Read More thumbnail image: Hydrophilic interactions change along with volume fractions

Weighing up ways of working out log P

Date: Jul 15, 2017

Author: Ryan De Vooght-Johnson

Lipophilicity is a key parameter affecting the activity of potential drug molecules, but there are many methods to calculate it. Scientists from the University of Belgrade examined various techniques for calculating the lipophilicity of a number of benzothiepino[3,2-c]pyridine derivatives, which were potential antifungal drugs.

Read More thumbnail image: Weighing up ways of working out log P

Journal Highlight: Synergetic use of principal component analysis applied to normed physicochemical measurements and GC × GC-MS to reveal the stabilization effect of selected essential oils on heated rapeseed oil

Date: Jul 10, 2017

Author: separationsNOW

The potential antioxidant effect of corainder and nutmeg essential oils on the thermal stability of rapeseed oil was determined by GCxGC/MS with PCA.

Read More thumbnail image: Journal Highlight Synergetic use of principal component analysis applied to normed physicochemical measurements and GC  GC-MS to reveal the stabilization effect of selected essential oils on heated rapeseed oil

DEREK peers at plethora of products in rat urine

Date: Jul 1, 2017

Author: Ryan De Vooght-Johnson

Fluvastatin is a commonly used statin compound, so it is important to carefully study its metabolites. Researchers based at the National Institutes of Pharmaceutical Education and Research in Hyderabad and S.A.S Nagar examined the metabolites of fluvastatin formed in vivo by rats, along with those formed in vitro by human or rat liver microsomes, using UHPLC-MS/MS. They subsequently ran in silico toxicity studies on these compounds.

Read More thumbnail image: DEREK peers at plethora of products in rat urine

From heartbreak to happiness with in-house MS database

Date: Jun 15, 2017

Author: Ryan De Vooght-Johnson

Gelsemium elegans is a toxic plant of interest for its possible medical uses. Scientists from Hunan Agricultural University in China used a combination of LC-MS/MS and an in-house database of the accurate masses of previously detected Gelsemium compounds to tentatively identify a wide range of the many components in a crude extract from the plant.

Read More thumbnail image: From heartbreak to happiness with in-house MS database

Journal Highlight: Essential-oil inspired synthetic libraries: synthesis, spectral and gas-chromatographic properties of new fenchyl esters

Date: Jun 5, 2017

Author: separationsNOW

The design, synthesis, and GC and NMR spectral characterization of a library of 32 endo- and exo-fenchyl esters have been described in work which will facilitate future essential oil analyses, especially those involving minor constituents.

Read More thumbnail image: Journal Highlight Essential-oil inspired synthetic libraries synthesis spectral and gas-chromatographic properties of new fenchyl esters
Page:   Prev 1 2 3 4 5 6 7 Next

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Copyright Information

Interested in spectroscopy? Visit our sister site spectroscopyNOW.com

Copyright © 2017 John Wiley & Sons, Inc. All Rights Reserved