Lab Informatics / Ezine

Skip to Navigation

Read our ezines for:

  • Review and analysis articles written by our team of renowned contributors.
  • Free access to journal articles on Wiley Online Library, selected by the website editor.
  • "Client Column" articles written by experts from spectroscopy and separation science industrial companies.

Ezine RSS Feed

rss

Filter Ezines

Browse By Ezines

Filter by Supplier

Browse By Supplier

Journal Highlight: Intra‐clade metabolomic profiling of MAR4 Streptomyces from the Macaronesia Atlantic region reveals a source of anti‐biofilm metabolites

Date: Feb 12, 2019

Author: separationsNOW

Hybrid isoprenoids from six MAR4 Streptomyces strains isolated from the Madeira Archipelago were studied by LC‐MS/MS and their metabolomic profiles were compared using multivariate statistical analysis in the search for metabolites that inhibit biofilm production in clinically and commercially important biofilm-forming bacteria.

Read More thumbnail image: Journal Highlight Intraclade metabolomic profiling of MAR4 Streptomyces from the Macaronesia Atlantic region reveals a source of antibiofilm metabolites

PeakMaster program predicts peak positions in electrophoresis

Date: Feb 5, 2019

Author: Ryan De Vooght-Johnson

Theoretical descriptions of electrophoresis have been implemented in computer simulation programs, but improvements to these are needed to adequately represent the conditions used in practice. A multi-centre team of researchers, from Charles University (Prague), Agilent Technologies (Waldbronn, Germany) and the CIMEC institute (Santa Fe, Argentina), have developed an improved model for electrophoresis, applying it to the electrokinetic chromatography (EKC) variant of capillary zone electrophoresis (CZE)...

Read More thumbnail image: PeakMaster program predicts peak positions in electrophoresis

Drug detection is augmented when MS networks implemented

Date: Jan 22, 2019

Author: Ryan De Vooght-Johnson

Toxicology laboratories have to deal with a huge number of drugs and other compounds, including some, such as new psychoactive substances (NPSs), where standard samples and even library data may not be readily available. Scientists from the University Hospital of Rennes (France) and the University of Geneva used molecular networking software, which identifies similarities in spectral data, on LC-MS/MS results from three different toxicology cases.

Read More thumbnail image: Drug detection is augmented when MS networks implemented

Journal Highlight: Automated optimization of XCMS parameters for improved peak picking of liquid chromatography–mass spectrometry data using the coefficient of variation and parameter sweeping for untargeted metabolomics

Date: Jan 14, 2019

Author: separationsNOW

A study of peak picking and processing of high‐resolution LC–MS metabolomics data using XCMS suggested that peak picking needs to be individually adapted for the experimental set up.

Read More thumbnail image: Journal Highlight Automated optimization of XCMS parameters for improved peak picking of liquid chromatographymass spectrometry data using the coefficient of variation and parameter sweeping for untargeted metabolomics

Keeping up in today’s drug race with the mzCloud database

Date: Jan 9, 2019

Author: Ryan De Vooght-Johnson

The increasing numbers of new psychoactive substances, otherwise known as ‘designer drugs’, pose a challenge both to medical professionals treating drug users and to law enforcement agencies. A multi-centre team, from the University of Versailles Saint-Quentin (Paris), neighbouring hospitals, Thermo Fisher (San Jose, California) and HighChem,(Bratislava, Slovakia), looked at a new method of examining hair samples for multiple drugs with LC-MS/MS, using data-dependent analysis (DDA) and the shared mzCloud...

Read More thumbnail image: Keeping up in todays drug race with the mzCloud database

Journal Highlight: A method that accounts for differential detectability in mixed samples of long‐term infections with applications to the case of chronic wasting disease in cervids

Date: Dec 17, 2018

Author: separationsNOW

A stochastic scenario tree model of diagnostic sensitivity for chronic wasting disease in cervids based on the ELISA detection of prion protein has been developed and applied to the recent emergence of the disease in a European population of reindeer.

Read More thumbnail image: Journal Highlight A method that accounts for differential detectability in mixed samples of longterm infections with applications to the case of chronic wasting disease in cervids

Journal Highlight: Trimethylamine N‐oxide as a risk marker for ischemic stroke in patients with atrial fibrillation

Date: Dec 5, 2018

Author: separationsNOW

Univariate and multivariate logistic regression analysis has shown that trimethylamine N‐oxide levels, measured in plasma by LC/MS/MS, are an independent predictor of ischemic stroke.

Read More thumbnail image: Journal Highlight Trimethylamine Noxide as a risk marker for ischemic stroke in patients with atrial fibrillation

Journal Highlight: Denaturing high‐performance liquid chromatography and principal component analysis for identification of DNA point mutations in breast cancer and lymphoma samples

Date: Nov 5, 2018

Author: separationsNOW

Principal component analysis has been used to analyze the HPLC chromatograms from 3 different genes acquired under denaturing conditions to identify point mutations.

Read More thumbnail image: Journal Highlight Denaturing highperformance liquid chromatography and principal component analysis for identification of DNA point mutations in breast cancer and lymphoma samples

Journal Highlight: Visualization and application of amino acid retention coefficients obtained from modeling of peptide retention

Date: Oct 8, 2018

Author: separationsNOW

A simple method for data inspection in liquid separations of peptides, especially multidimensional separations, using amino acid retention coefficients and their relative change across experiments improves comparability of data at no additional experimental cost.

Read More thumbnail image: Journal Highlight Visualization and application of amino acid retention coefficients obtained from modeling of peptide retention

Journal Highlight: Biomarkers of individual foods, and separation of diets using untargeted LC–MS‐based plasma metabolomics in a randomized controlled trial

Date: Sep 10, 2018

Author: separationsNOW

The effect of the new Nordic diet versus average Danish diet on plasma metabolic profiles has been investigated by LC/MS to identify biomarkers of diet compliance and metabolic effects, using supervised machine learning with feature selection.

Read More thumbnail image: Journal Highlight Biomarkers of individual foods and separation of diets using untargeted LCMSbased plasma metabolomics in a randomized controlled trial
Page:   1 2 3 4 5 6 Next

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Copyright Information

Interested in spectroscopy? Visit our sister site spectroscopyNOW.com

Copyright © 2019 John Wiley & Sons, Inc. All Rights Reserved