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Quantification in LC and GC

Date: Sep 9, 2009

Author: Stavros Kromidas, Hans -Joachim Kuss

Closing a gap in the current literature by addressing the evaluation and quality assessment of raw data, this practice-oriented guide is clearly divided into three parts. The first describes basic considerations of chromatographic data quality, common errors and potential pitfalls in reading out and quantifying the data. Part two systematically covers the most important chromatographic methods as well as the specific requirements for obtaining good chromatographic data. The final part looks at data quality...

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Chemometrics for Pattern Recognition

Date: Aug 21, 2009

Author: Richard Brereton

Over the past decade, pattern recognition has been one of the fastest growth points in chemometrics. This has been catalysed by the increase in capabilities of automated instruments such as LCMS, GCMS, and NMR, to name a few, to obtain large quantities of data, and, in parallel, the significant growth in applications especially in biomedical analytical chemical measurements of extracts from humans and animals, together with the increased capabilities of desktop computing. The interpretation of such...

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Miniaturization of Analytical Systems: Principles, Designs and Applications

Date: Aug 14, 2009

Author: Angel Rios, Alberto Escarpa, Bartolome Simonet

The book describes a general vision of the miniaturization of the analytical systems, including their principles, designs and applications. Through ten chapters the different aspects characterizing the miniaturized systems are developed. Thus, the two first chapters include the basic concepts behind miniaturization in analytical chemistry, as well as the mechanical and electronic tools needed for designing and fabricating miniaturized analytical systems.  Chapters 3 to 6 represent the core of the...

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Basic Gas Chromatography, 2nd Edition

Date: Jul 17, 2009

Author: Harold M. McNair, James M. Miller

The New Edition of the Well-Regarded Handbook on Gas Chromatography Since the publication of the highly successful first edition of Basic Gas Chromatography, the practice of chromatography has undergone several notable developments. Basic Gas Chromatography, Second Edition covers the latest in the field, giving readers the most up-to-date guide available, while maintaining the first edition's practical, applied approach to the subject and its accessibility to a wide range of readers. The text provides...

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Liquid Chromatography Time-of-Flight Mass Spectrometry

Date: Apr 23, 2009

Author: Imma Ferrer, E. M. Thurman

Time of flight mass spectrometry identifies the elements of a compound by subjecting a sample of ions to a strong electrical field. Illuminating emerging analytical techniques in high-resolution mass spectrometry, Liquid Chromatography Time-of-Flight Mass Spectrometry shows readers how to analyze unknown and emerging contaminants—such as antibiotics, steroids, analgesics—using advanced mass spectrometry techniques. The text combines theoretical discussion with concrete examples, making it...

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Nano Chromatography and Capillary Electrophoresis: Pharmaceutical and Environmental Analyses

Date: Apr 21, 2009

Author: Imran Ali, Hassan Y. Aboul-Enein

Detection of drugs at low concentration is required in a variety of biological and medical situations, in order to avoid harmful side effects posed by some drug residues. The book details the instrumentation, detection, and application of nano chromatography (that is, any chromatographic and capillary electrophoretic method dealing with the detection of a sample at nano gram per liter or lower) and capillary electrophoresis in the analyses of biological and environmental samples. Methods discussed include:...

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Medical Imaging: Principles, Detectors, and Electronics

Date: Apr 9, 2009

Author: Krzysztof Iniewski

A must-read for anyone working in electronics in the healthcare sector This one-of-a-kind book addresses state-of-the-art integrated circuit design in the context of medical imaging of the human body. It explores new opportunities in ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), nuclear medicine (PET, SPECT), emerging detector technologies, circuit design techniques, new materials, and innovative system approaches. Divided into four clear parts and with contributions from a...

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Introduction to Proteomics

Date: Nov 7, 2008

Author: Agnieszka Kraj, Jerzy Silberring

Introduction to Proteomics is written by seasoned researchers with years of practical experience. In addition to comprehensive discussions of the basic concepts, techniques, and applications of the subject, the text also includes an extensive glossary and a chapter containing laboratory exercises and protocols. While mass spectrometry is central to proteomics, the book discusses all of the analytical techniques a student is likely to need when faced with real-world problems, such as sample preparation,...

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Preclinical Development Handbook: ADME and Biopharmaceutical Properties

Date: Apr 29, 2008

Author: Shayne Cox Gad

A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for...

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Multidimensional Liquid Chromatography: Theory and Applications in Industrial Chemistry and the Life Sciences

Date: Apr 22, 2008

Author: Steven A. Cohen, Mark R. Schure

Multidimensional Liquid Chromatography (MDLC) is a very powerful separation technique for analyzing exceptionally complex samples in one step. This authoritative reference presents a number of recent contributions that help define the current art and science of MDLC. Topics covered include instrumentation, theory, methods development, and applications of MDLC in the life sciences and in industrial chemistry. With the information to help you perform very difficult separations of complex samples, this...

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