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Thinking inside the box: A novel alternative to preparative chromatography

Date: Apr 9, 2018

Author: Jon Evans

Canadian researchers show that a box filled with ion-exchange particles offers a more efficient way to purify protein-based biopharmaceuticals than conventional preparative chromatography.

Read More thumbnail image: Thinking inside the box A novel alternative to preparative chromatography

Journal Highlight: Separation and determination of polyurethane amine catalysts in polyether polyols by using UHPLC–Q‐TOF‐MS on a reversed‐phase/cation‐exchange mixed‐mode column

Date: Mar 26, 2018

Author: separationsNOW

Chinese scientists have used a reversed‐phase/cation‐exchange mixed‐mode chromatography column, with mass spectrometry, to analyze polyurethane amine catalysts in polyether polyols.

Read More thumbnail image: Journal Highlight Separation and determination of polyurethane amine catalysts in polyether polyols by using UHPLCQTOFMS on a reversedphasecationexchange mixedmode column

The joy of SAXS: When combined with ion-exchange chromatography

Date: Mar 12, 2018

Author: Jon Evans

By taking advantage of a micro-ionization chamber, a Japanese scientist has been able to combine small-angle X-ray scattering with ion-exchange chromatography to produce a new method for characterizing proteins.

Read More thumbnail image: The joy of SAXS When combined with ion-exchange chromatography

Journal Highlight: Glycosyltransferase cascades made fit for chemical production: Integrated biocatalytic process for the natural polyphenol C-glucoside nothofagin

Date: Mar 5, 2018

Author: separationsNOW

Austrian scientists used anion-exchange chromatography to capture and purify a glycosylated biomolecule produced by a novel glycosyltransferase reaction cascade.

Read More thumbnail image: Journal Highlight Glycosyltransferase cascades made fit for chemical production Integrated biocatalytic process for the natural polyphenol C-glucoside nothofagin

Journal Highlight: Simple determination of betaine, L-carnitine and choline in human urine using self-packed column and column-switching ion chromatography with nonsuppressed conductivity detection

Date: Feb 26, 2018

Author: separationsNOW

Chemists in China have used column-switching ion chromatography to analyze the quaternary ammonium salts betaine, L-carnitine and choline in human urine.

Read More thumbnail image: Journal Highlight Simple determination of betaine L-carnitine and choline in human urine using self-packed column and column-switching ion chromatography with nonsuppressed conductivity detection

Do feed the animals: An IC method for detecting phosphorus and sulfur in animal feed

Date: Feb 12, 2018

Author: Jon Evans

A novel ion chromatography method for detecting phosphorus and sulfur in animal feed is not only greener than current recommended methods, but also faster, cheaper and more sensitive.

Read More thumbnail image: Do feed the animals An IC method for detecting phosphorus and sulfur in animal feed

Journal Highlight: Effects of hemoglobin variants HbJ Bangkok, HbE, HbG Taipei, and HbH on analysis of glycated hemoglobin via ion-exchange HPLC

Date: Feb 5, 2018

Author: separationsNOW

Chinese researchers have found that certain hemoglobin variants can cause interference in the analysis of glycated hemoglobin by ion-exchange high-performance liquid chromatography.

Read More thumbnail image: Journal Highlight Effects of hemoglobin variants HbJ Bangkok HbE HbG Taipei and HbH on analysis of glycated hemoglobin via ion-exchange HPLC

Journal Highlight: Quantification of the pyrrolizidine alkaloid jacobine in Crassocephalum crepidioides by cation exchange high-performance liquid chromatography

Date: Jan 22, 2018

Author: separationsNOW

Scientists from Germany and Nigeria have tested the suitability of cation exchange chromatography for separating pyrrolizidine alkaloids from other plant metabolites extracted from a herb called Crassocephalum crepidioides.

Read More thumbnail image: Journal Highlight Quantification of the pyrrolizidine alkaloid jacobine in Crassocephalum crepidioides by cation exchange high-performance liquid chromatography

Beneficial bream bacteria biosurfactants: Analyzing bioactive compounds in bream guts

Date: Jan 8, 2018

Author: Jon Evans

Using various analytical techniques, including thin-layer chromatography, Italian scientists have discovered that certain bacteria in the guts of sea bream can produce biosurfactants with some highly useful properties.

Read More thumbnail image: Beneficial bream bacteria biosurfactants Analyzing bioactive compounds in bream guts

Journal Highlight: Characterization of a robust serine protease from Bacillus subtilis K-1

Date: Jan 5, 2018

Author: separationsNOW

Researchers in India used ion-exchange chromatography and size-exclusion chromatography to extract and purify a robust protease from the bacterium Bacillus subtilis.

Read More thumbnail image: Journal Highlight Characterization of a robust serine protease from Bacillus subtilis K-1
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