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Mining for the metals inside plants

Date: Jun 1, 2016

Author: Ryan De Vooght-Johnson

As well as oxygen and water, plants also need metals to survive. Detecting these metals is a major challenge in the plant sciences, and no technique has so far been able to profile all the metals inside a plant. A study in New Phytologist describes a revolutionary new method that was able to detect a wide range of metals – including iron, copper, zinc and nickel – inside the pea plant.

Read More thumbnail image: Mining for the metals inside plants

Journal Highlight: LogP measurement of a highly hydrophobic properfume: evaluation of extrapolation of RP-HPLC results and impact of chemical moieties on accuracy

Date: May 23, 2016

Author: separationsNOW

The LogP of properfume Haloscent®D was measured by RP-HPLC using an indirect method involving its relationship with the retention factor and careful selection of suitable standards.

Read More thumbnail image: Journal Highlight LogP measurement of a highly hydrophobic properfume evaluation of extrapolation of RP-HPLC results and impact of chemical moieties on accuracy

The antioxidant’s nightmare: Xanthine oxidoreductase

Date: May 15, 2016

Author: Ryan De Vooght-Johnson

Xanthine oxidoreductase is an enzyme with important roles in the body. However, it also produces harmful free radicals that can damage cells. A new method to detect its activity could accelerate research into major diseases including diabetes and heart disease.

Read More thumbnail image: The antioxidants nightmare Xanthine oxidoreductase

Microbial chatter: how bacteria talk to each other

Date: May 1, 2016

Author: Ryan De Vooght-Johnson

By secreting tiny signalling molecules, bacteria coordinate their activity for best effect. A study published in Israel’s Journal of Chemistry describes the signalling molecules secreted by a bacterium found in the depths of the Mediterranean Sea.

Read More thumbnail image: Microbial chatter how bacteria talk to each other

Journal Highlight: High-performance liquid chromatographic resolution of neutral and cationic hetero[6]helicenes

Date: Apr 25, 2016

Author: separationsNOW

The enantiomeric separation of recently synthesised cationic hetero[6]helicenes has been accomplished by HPLC with different types of columns.

Read More thumbnail image: Journal Highlight High-performance liquid chromatographic resolution of neutral and cationic hetero6helicenes

Exposing the toxic whitening agents in food packaging

Date: Apr 14, 2016

Author: Ryan De Vooght-Johnson

Some chemicals used to make food packaging appear whiter can have toxic effects if ingested. A study newly published in the Journal of Separation Science describes a simple method to detect them, based on high-performance liquid chromatography with an ionic solvent.

Read More thumbnail image: Exposing the toxic whitening agents in food packaging

Drugs in drinking water

Date: Apr 7, 2016

Author: Ryan De Vooght-Johnson

If not properly removed from wastewater, drugs can end up in rivers, streams and even drinking water. A new study from Sweden analysed the chemicals formed when beta blockers were broken down by wetlands, revealing a wide range of transformation products, including several never-before described compounds.

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MB327: antidote to a deadly nerve agent

Date: Mar 21, 2016

Author: Ryan De Vooght-Johnson

Organophosphates are toxic nerve agents, also found in smaller doses in pesticides. For the first time, researchers have quantified a promising new antidote to organophosphate poisoning in blood samples. The results shed new light on the pharmacokinetic properties of the drug, which is currently under pre-clinical development.

Read More thumbnail image: MB327 antidote to a deadly nerve agent

Journal Highlight: Pressurized liquid extraction followed by liquid chromatography with tandem mass spectrometry to determine pharmaceuticals in mussels

Date: Mar 21, 2016

Author: separationsNOW

Pressurized liquid extraction and SPE followed by liquid chromatography with electrospray ionization and tandem mass spectrometry were used for the determination of seven widely used pharmaceuticals in mussel species.

Read More thumbnail image: Journal Highlight Pressurized liquid extraction followed by liquid chromatography with tandem mass spectrometry to determine pharmaceuticals in mussels

Next-generation sports drug testing

Date: Mar 16, 2016

Author: Ryan De Vooght-Johnson

Diuretics are important doping agents. Although they have no performance-enhancing effects, they can mask the intake of drugs that do, including steroids. A study from Norway reports a sensitive method for detecting diuretics in urine, which extends the detection window by a factor of six.

Read More thumbnail image: Next-generation sports drug testing
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