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Drugs in drinking water

Date: Apr 7, 2016

Author: Ryan De Vooght-Johnson

If not properly removed from wastewater, drugs can end up in rivers, streams and even drinking water. A new study from Sweden analysed the chemicals formed when beta blockers were broken down by wetlands, revealing a wide range of transformation products, including several never-before described compounds.

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MB327: antidote to a deadly nerve agent

Date: Mar 21, 2016

Author: Ryan De Vooght-Johnson

Organophosphates are toxic nerve agents, also found in smaller doses in pesticides. For the first time, researchers have quantified a promising new antidote to organophosphate poisoning in blood samples. The results shed new light on the pharmacokinetic properties of the drug, which is currently under pre-clinical development.

Read More thumbnail image: MB327 antidote to a deadly nerve agent

Journal Highlight: Pressurized liquid extraction followed by liquid chromatography with tandem mass spectrometry to determine pharmaceuticals in mussels

Date: Mar 21, 2016

Author: separationsNOW

Pressurized liquid extraction and SPE followed by liquid chromatography with electrospray ionization and tandem mass spectrometry were used for the determination of seven widely used pharmaceuticals in mussel species.

Read More thumbnail image: Journal Highlight Pressurized liquid extraction followed by liquid chromatography with tandem mass spectrometry to determine pharmaceuticals in mussels

Next-generation sports drug testing

Date: Mar 16, 2016

Author: Ryan De Vooght-Johnson

Diuretics are important doping agents. Although they have no performance-enhancing effects, they can mask the intake of drugs that do, including steroids. A study from Norway reports a sensitive method for detecting diuretics in urine, which extends the detection window by a factor of six.

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Journal Highlight: Time-resolved fluorescence HPLC detection using semiconductor light sources: Principles and applications

Date: Feb 22, 2016

Author: separationsNOW

An HPLC system incorporating real-time time-resolved fluorescence counting with on-the-fly data evaluation and typical chromatogram displays has been developed, using semiconductor light sources for ns resolution.

Read More thumbnail image: Journal Highlight Time-resolved fluorescence HPLC detection using semiconductor light sources Principles and applications

Deconstructing dyes: the colourings used in historical artworks

Date: Feb 12, 2016

Author: Ryan De Vooght-Johnson

Plant extracts have been used as dyes for over 5000 years and are behind some of history’s greatest artworks. In a new study, researchers report a HPLC-based method to identify natural dyes, applied to an ancient Italian carpet.

Read More thumbnail image: Deconstructing dyes the colourings used in historical artworks

What’s really in your skin cream?

Date: Feb 1, 2016

Author: Ryan De Vooght-Johnson

The growing trend for functional cosmetics, dubbed ‘cosmeceuticals’, includes anti-wrinkle and skin whitening creams. A liquid chromatography-driven technique has been used to detect the active compounds in these products, helping to provide quality control for the emerging market.

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Journal Highlight: Determination of lutein from fruit and vegetables through an alkaline hydrolysis extraction method and HPLC analysis

Date: Jan 25, 2016

Author: separationsNOW

A simple and rapid HPLC method for the determination of lutein content, successfully used for cereal matrices, was evaluated in fruit and vegetables.

Read More thumbnail image: Journal Highlight Determination of lutein from fruit and vegetables through an alkaline hydrolysis extraction method and HPLC analysis

Blood test could predict prognosis for prostate cancer

Date: Jan 13, 2016

Author: Ryan De Vooght-Johnson

Accurate prostate cancer staging is important for selecting the best treatment, but currently requires biopsy. A study newly published in The Prostate describes markers in blood, measured by LC-MS/MS, which correlate with the stage of the disease and may be useful for predicting prognosis.

Read More thumbnail image: Blood test could predict prognosis for prostate cancer

Closing the door on drug-facilitated crimes: detecting “date rape” drugs in drinks

Date: Jan 1, 2016

Author: Ryan De Vooght-Johnson

Benzodiazepines are effectively used to treat anxiety and insomnia, but are frequently hijacked for illegal purposes. A method for their rapid detection in alcoholic beverages is reported by a new paper, which has implications for trials for drug-related crime.

Read More thumbnail image: Closing the door on drug-facilitated crimes detecting date rape drugs in drinks
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