HPLC @ separationsNOW

The HPLC channel covers all techniques used for the separation of liquids.

This includes multidimensional techniques (e.g. LCxLC) and hyphenated techniques (e.g. LC-MS). Also included are capillary LC, nano LC, SEC (Size Exclusion Chromatography) and GPC (Gel Permeation Chromatography).

Gas Chromatography

Monthly Highlight

Last Month's Most Accessed Feature: LC on a nano-scale measures steroids in the whale

Measurements of the levels of steroid hormones in live whales is crucial to understanding their health and breeding capacity. Researchers from Texas Tech University and the University of Alaska Fairbanks have devised a novel nano-LC-MS/MS method of steroid analysis that requires smaller blubber samples than existing techniques.

Read More thumbnail image: Last Month's Most Accessed Feature: LC on a nano-scale measures steroids in the whale

Now available on-demand
Analysis of Environmental Contaminants in Water Using an Agilent 6470 LC/TQ Instrument

The analytical demands for detecting organic contaminants in water at low ng/L level have pushed the development of new methodologies using LC/TQ instrumentation. In this regard, and in the last few years, advances in sensitivity and selectivity have made this challenge possible. This webinar will focus on the use of the new 6470 LC-MS-MS from Agilent Technologies for the sub ng/L level detection of several pharmaceuticals and pesticides in surface waters. Examples of optimization of several source...

Read More thumbnail image: <font color=red>Webinar<br/>Now available on-demand<br/></font>Analysis of Environmental Contaminants in Water Using an Agilent 6470 LC/TQ Instrument

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JMS Special Feature Collections

thumbnail image: <font size=3>JMS Special Feature Collections</font>

For over 20 years, each issue of the Journal of Mass Spectrometry has contained a Special Feature article. These are highly regarded in the mass spectrometry community and extremely popular with researchers around the globe. These features are freely available to the entire mass spec community.

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LC-MS/MS detects dangerously doped drivers

Ryan De Vooght-Johnson

Aug 15, 2017

thumbnail image: LC-MSMS detects dangerously doped drivers

The detection of the levels of cannabis compounds and their metabolites is an important challenge to both medical practitioners and law enforcement agencies. Scientists from the National Institute of Drug Abuse (NIDA) in Baltimore have developed a new method to assay these compounds using enzymatic hydrolysis followed by LC-MS/MS.

Monoclonal measured by means of peptide marker

Ryan De Vooght-Johnson

Aug 1, 2017

thumbnail image: Monoclonal measured by means of peptide marker

Monoclonal antibodies are being increasingly used to treat a wide range of diseases, but quantification of their concentrations in blood remains a challenge. Researchers from Naples have used LC-MS to detect a characteristic peptide fragment from the anticancer monoclonal antibody trastuzumab (Herceptin) in order to determine its serum concentration.

37 Antibiotics from different classes have been measured in three different farmed fish species by a novel LC-MS/MS method, revealing potential public health concerns.

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Selected key technologies of the analytical science industry are discussed by Steve Down with reference to burgeoning application areas and the scope for future improvements.

Ion source pressure plays a significant role in the process of ionization and the subsequent ion transmission inside a mass spectrometer. Pressurizing the ion source to a gas pressure greater than atmospheric pressure is a relatively new approach that aims to further improve the performance of atmospheric pressure ionization sources. A brief review on the development of super-atmospheric pressure ion sources, including high-pressure electrospray, field desorption and superheated ESI, and the strategies to...

In the current context of international conflicts and localized terrorist actions, there is unfortunately a permanent threat of attacks with unconventional warfare agents. Among these, biological agents such as toxins, microorganisms, and viruses deserve particular attention owing to their ease of production and dissemination. Mass spectrometry-based techniques for the detection and quantification of biological agents have a decisive role to play for countermeasures in a scenario of biological attacks.

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The Journal of Mass Spectrometry (JMS) publishes papers on a broad range of topics of interest to scientists working in both fundamental and applied areas involving the study of gaseous ions.

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