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Journal Highlight: Effects of formalin fixation and temperature on MR relaxation times in the human brain

Date: Apr 11, 2016

Author: separationsNOW

Austrian researchers used gel electrophoresis, along with several other analytical techniques, to investigate the effect of formalin fixation on magnetic resonance relaxation times in the human brain.

Read More thumbnail image: Journal Highlight Effects of formalin fixation and temperature on MR relaxation times in the human brain

Journal Highlight: Chiral separation of uncharged pomalidomide enantiomers using carboxymethyl-β-cyclodextrin: a validated capillary electrophoretic method

Date: Mar 28, 2016

Author: separationsNOW

For the first time, scientists in Romania and Hungary have used capillary zone electrophoresis to separate a racemic mixture of pomalidomide, a second-generation immunomodulatory uncharged drug.

Read More thumbnail image: Journal Highlight Chiral separation of uncharged pomalidomide enantiomers using carboxymethyl--cyclodextrin a validated capillary electrophoretic method

Resolving the mystery of time: A novel way to increase the sensitivity of difference 2-DE

Date: Mar 21, 2016

Author: Jon Evans

By recording how fluorescence decays over time, scientists from Sweden and Germany have managed to increase the sensitivity of difference 2D gel electrophoresis by up to 8000 times.

Read More thumbnail image: Resolving the mystery of time A novel way to increase the sensitivity of difference 2-DE

Journal Highlight: Development of fully automated quantitative capillary electrophoresis with high accuracy and repeatability

Date: Mar 14, 2016

Author: separationsNOW

Chinese scientists have developed a fully-automated quantitative capillary electrophoresis system by utilizing a rotary type of nano-volume injector, an autosampler and a thermostat with cooling capacity.

Read More thumbnail image: Journal Highlight Development of fully automated quantitative capillary electrophoresis with high accuracy and repeatability

Journal Highlight: Leaf proteome comparison of two GM common bean varieties and their non-GM counterparts by principal component analysis

Date: Feb 22, 2016

Author: separationsNOW

Brazilian food scientists have used 2D gel electrophoresis and principal component analysis to compare the proteomic profile of a genetically-modified (GM) common bean and its non-GM counterpart.

Read More thumbnail image: Journal Highlight Leaf proteome comparison of two GM common bean varieties and their non-GM counterparts by principal component analysis

Structural damage: Analyzing heparin with CE-MS

Date: Feb 15, 2016

Author: Jon Evans

A novel CE-MS method for analyzing the molecular structure of the anticoagulant heparin should help prevent the severe allergic reactions that led to many deaths several years ago.

Read More thumbnail image: Structural damage Analyzing heparin with CE-MS

Journal Highlight: Proteomic responses of human intestinal Caco-2 cells exposed to silver nanoparticles and ionic silver

Date: Feb 8, 2016

Author: separationsNOW

German researchers have used two-dimensional gel electrophoresis with MALDI mass spectrometry to conduct a proteomic study into the effect of silver nanoparticles on human intestinal cells.

Read More thumbnail image: Journal Highlight Proteomic responses of human intestinal Caco-2 cells exposed to silver nanoparticles and ionic silver

Journal Highlight: The use of PCR-DGGE to determine bacterial fingerprints for poultry and red meat abattoir effluent

Date: Jan 25, 2016

Author: separationsNOW

A South African food scientist has used denaturing gradient gel electrophoresis to determine the bacteria present in effluent originating from abattoirs slaughtering different animal species.

Read More thumbnail image: Journal Highlight The use of PCR-DGGE to determine bacterial fingerprints for poultry and red meat abattoir effluent

The weakest linker: Testing the stability of novel DNA structures

Date: Jan 18, 2016

Author: Jon Evans

Investigating the properties of various different linkers for constructing novel DNA structures required German chemists to use gel electrophoresis at almost every stage in the process.

Read More thumbnail image: The weakest linker Testing the stability of novel DNA structures

Journal Highlight: Effect of processing techniques on the 3D microstructure of poly(lactic acid) scaffolds reinforced with wool keratin from different sources

Date: Jan 5, 2016

Author: separationsNOW

Italian researchers have used gel electrophoresis to help investigate how processing affects the microstructure of poly(lactic acid) scaffolds reinforced with keratin derived from wool.

Read More thumbnail image: Journal Highlight Effect of processing techniques on the 3D microstructure of polylactic acid scaffolds reinforced with wool keratin from different sources
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