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Sequence of pillars: Produces fastest ever separation of DNA and RNA

Date: Apr 17, 2017

Author: Jon Evans

Using nanopillars in a nanoslit, a team of Japanese scientists has achieved the fastest ever separation of nucleic acids by microchip electrophoresis, separating micro-RNA from DNA in just 20 microseconds.

Read More thumbnail image: Sequence of pillars Produces fastest ever separation of DNA and RNA

Journal Highlight: Ruthenium(II)–arene metallacycles: Crystal structures, interaction with DNA, and cytotoxicity

Date: Apr 10, 2017

Author: separationsNOW

Chemists in China and the UK used gel electrophoresis to investigate how 24 newly-synthesized ruthenium metallamacrocycles interact with DNA.

Read More thumbnail image: Journal Highlight RutheniumIIarene metallacycles Crystal structures interaction with DNA and cytotoxicity

Journal Highlight: Proteomic maps of subcellular protein fractions of the Asian citrus psyllid Diaphorina citri, the vector of citrus huanglongbing

Date: Mar 27, 2017

Author: separationsNOW

Scientists in the US have used 2D gel electrophoresis to produce subcellular proteomic profiles of a major insect pest of citrus plants.

Read More thumbnail image: Journal Highlight Proteomic maps of subcellular protein fractions of the Asian citrus psyllid Diaphorina citri the vector of citrus huanglongbing

Running hot and cold: Analyzing oligosaccharides with temperature gradient CE

Date: Mar 20, 2017

Author: Jon Evans

Varying the operational temperature could offer a simple way to improve the resolution when separating oligosaccharides by capillary electrophoresis.

Read More thumbnail image: Running hot and cold Analyzing oligosaccharides with temperature gradient CE

Journal Highlight: Nitrate and nitrite determination in gunshot residue samples by CE in acidic run buffer

Date: Mar 13, 2017

Author: separationsNOW

Turkish chemists have developed a capillary electrophoresis method for conducting the simultaneous determination of nitrate and nitrite in gunshot residue.

Read More thumbnail image: Journal Highlight Nitrate and nitrite determination in gunshot residue samples by CE in acidic run buffer

Journal Highlight: Identification and changes in the seasonal concentrations of heat shock proteins in roe deer epididymides

Date: Feb 27, 2017

Author: separationsNOW

Polish scientists have used two-dimensional gel electrophoresis to investigate the expression of heat shock proteins in the reproductive tract of mature roe deer during the mating seaseon.

Read More thumbnail image: Journal Highlight Identification and changes in the seasonal concentrations of heat shock proteins in roe deer epididymides

Taking charge of PTMs: Studying post-translational modifications with CE-MS

Date: Feb 20, 2017

Author: Jon Evans

Because post-translational modifications often alter the net charge of their host peptide or protein, CE-MS turns out to be a highly effective technique for learning more about them.

Read More thumbnail image: Taking charge of PTMs Studying post-translational modifications with CE-MS

Journal Highlight: Protein charge determination and implications for interactions in cell extracts

Date: Feb 13, 2017

Author: separationsNOW

Scientists in the US and Ireland used gel electrophoresis to investigate the charge of the protein cytochrome c in buffer and Escherichia coli extracts.

Read More thumbnail image: Journal Highlight Protein charge determination and implications for interactions in cell extracts

Journal of Separation Science Celebrates 40th Volume

Date: Feb 8, 2017

Author:

The Journal of Separation Science was born in 1978 with the name, Journal of High Resolution Chromatography, and this year celebrates its 40th birthday. To celebrate, we've created a virtual issue containing the journal's top 40 cited papers over the last four decades; and it's free for you to read for the whole of 2017.

Read More thumbnail image: Journal of Separation Science Celebrates 40th Volume

Journal Highlight: A parallel stranded G-quadruplex composed of threose nucleic acid (TNA)

Date: Jan 23, 2017

Author: separationsNOW

Scientists in the US have used gel electrophoresis, circular dichroism and NMR spectroscopy to investigate the potential for threose nucleic acid to adopt a four-stranded helical structure.

Read More thumbnail image: Journal Highlight A parallel stranded G-quadruplex composed of threose nucleic acid TNA
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