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Didn’t feel a thing: Novel CE-MS method for analyzing metabolites in live cells

Date: May 15, 2017

Author: Jon Evans

A newly-developed CE-MS method has allowed US scientists to analyze the metabolites in live frog embryo cells, providing unprecedented molecular insight into embryo development.

Read More thumbnail image: Didnt feel a thing Novel CE-MS method for analyzing metabolites in live cells

Journal Highlight: Monitoring of the bacterial communities of bamboo shoots (Dendrocalamus latiflorus) during pickling process

Date: May 8, 2017

Author: separationsNOW

Chinese scientists have used denaturing gradient gel electrophoresis and the polymerase chain reaction to investigate the diversity and dynamics of the dominant bacterial communities that arise during the pickling of bamboo shoots.

Read More thumbnail image: Journal Highlight Monitoring of the bacterial communities of bamboo shoots Dendrocalamus latiflorus during pickling process

Journal Highlight: The occurrence of spoilage yeasts in cream-filled bakery products

Date: Apr 24, 2017

Author: separationsNOW

Italian scientists used denaturing gradient gel electrophoresis to help discover the yeasts responsible for spoiling a cream-filled baked product.

Read More thumbnail image: Journal Highlight The occurrence of spoilage yeasts in cream-filled bakery products

Sequence of pillars: Produces fastest ever separation of DNA and RNA

Date: Apr 17, 2017

Author: Jon Evans

Using nanopillars in a nanoslit, a team of Japanese scientists has achieved the fastest ever separation of nucleic acids by microchip electrophoresis, separating micro-RNA from DNA in just 20 microseconds.

Read More thumbnail image: Sequence of pillars Produces fastest ever separation of DNA and RNA

Journal Highlight: Ruthenium(II)–arene metallacycles: Crystal structures, interaction with DNA, and cytotoxicity

Date: Apr 10, 2017

Author: separationsNOW

Chemists in China and the UK used gel electrophoresis to investigate how 24 newly-synthesized ruthenium metallamacrocycles interact with DNA.

Read More thumbnail image: Journal Highlight RutheniumIIarene metallacycles Crystal structures interaction with DNA and cytotoxicity

Journal Highlight: Proteomic maps of subcellular protein fractions of the Asian citrus psyllid Diaphorina citri, the vector of citrus huanglongbing

Date: Mar 27, 2017

Author: separationsNOW

Scientists in the US have used 2D gel electrophoresis to produce subcellular proteomic profiles of a major insect pest of citrus plants.

Read More thumbnail image: Journal Highlight Proteomic maps of subcellular protein fractions of the Asian citrus psyllid Diaphorina citri the vector of citrus huanglongbing

Running hot and cold: Analyzing oligosaccharides with temperature gradient CE

Date: Mar 20, 2017

Author: Jon Evans

Varying the operational temperature could offer a simple way to improve the resolution when separating oligosaccharides by capillary electrophoresis.

Read More thumbnail image: Running hot and cold Analyzing oligosaccharides with temperature gradient CE

Journal Highlight: Nitrate and nitrite determination in gunshot residue samples by CE in acidic run buffer

Date: Mar 13, 2017

Author: separationsNOW

Turkish chemists have developed a capillary electrophoresis method for conducting the simultaneous determination of nitrate and nitrite in gunshot residue.

Read More thumbnail image: Journal Highlight Nitrate and nitrite determination in gunshot residue samples by CE in acidic run buffer

Journal Highlight: Identification and changes in the seasonal concentrations of heat shock proteins in roe deer epididymides

Date: Feb 27, 2017

Author: separationsNOW

Polish scientists have used two-dimensional gel electrophoresis to investigate the expression of heat shock proteins in the reproductive tract of mature roe deer during the mating seaseon.

Read More thumbnail image: Journal Highlight Identification and changes in the seasonal concentrations of heat shock proteins in roe deer epididymides

Taking charge of PTMs: Studying post-translational modifications with CE-MS

Date: Feb 20, 2017

Author: Jon Evans

Because post-translational modifications often alter the net charge of their host peptide or protein, CE-MS turns out to be a highly effective technique for learning more about them.

Read More thumbnail image: Taking charge of PTMs Studying post-translational modifications with CE-MS
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