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Seen in the pixels: Novel method for improving the sensitivity of fluorescence detection

Date: May 15, 2017

Author: Jon Evans

By taking advantage of the pixels in a charge-coupled device, Chinese scientists have come up with a simple way to improve the sensitivity of fluorescence-based detection.

Read More thumbnail image: Seen in the pixels Novel method for improving the sensitivity of fluorescence detection

Journal Highlight: Characterization of Ag and Au nanolayers on Cu alloys by TLC, SEM-EDS, and ICP-OES

Date: May 8, 2017

Author: separationsNOW

Chemists in Crotia have used a combination of thin-layer chromatography, scanning electron microscope-energy dispersive spectroscopy and inductively coupled plasma optical emission spectroscopy to analyze silver-plated and gilded copper alloys.

Read More thumbnail image: Journal Highlight Characterization of Ag and Au nanolayers on Cu alloys by TLC SEM-EDS and ICP-OES

Journal Highlight: Micellar liquid chromatographic determination of metformin hydrochloride using fluorimetric detection after pre-column derivatization

Date: May 3, 2017

Author: separationsNOW

Using a novel derivatization reaction, an Egyptian analytical chemist has been able to determine the type 2 diabetes drug metformin hydrochloride in human plasma with micellar liquid chromatography and fluorimetric detection.

Read More thumbnail image: Journal Highlight Micellar liquid chromatographic determination of metformin hydrochloride using fluorimetric detection after pre-column derivatization

Shedding light on drug delivery: Detecting protein-coated polymer particles

Date: Apr 17, 2017

Author: Jon Evans

Chinese chemists have come up with a novel method for coating polymer nanoparticles with proteins, which they assessed by studying the coated particles with several different analytical techniques.

Read More thumbnail image: Shedding light on drug delivery Detecting protein-coated polymer particles

Journal Highlight: Characterization of crude oil asphaltenes by coupling SEC directly to an ultrahigh-resolution MS

Date: Apr 10, 2017

Author: separationsNOW

German scientists have coupled Fourier transform Orbitrap mass spectrometry with size-exclusion chromatography to analyze the asphaltenes in crude oil.

Read More thumbnail image: Journal Highlight Characterization of crude oil asphaltenes by coupling SEC directly to an ultrahigh-resolution MS

Journal Highlight: A versatile and highly selective colorimetric sensor for the detection of amines

Date: Apr 6, 2017

Author: separationsNOW

Scientists in the US have developed a novel method for detecting amines by colorimetric detection after separation by thin-layer chromatography, which they've used to detect the volatile amines responsible for food spoilage in fish samples.

Read More thumbnail image: Journal Highlight A versatile and highly selective colorimetric sensor for the detection of amines

Propelled to the surface: Combining CE and ELISA for protein detection

Date: Mar 20, 2017

Author: Jon Evans

Researchers from China and Japan have shown how an enzyme-linked immunosorbent assay can act as an accurate and sensitive protein detection method for capillary electrophoresis.

Read More thumbnail image: Propelled to the surface Combining CE and ELISA for protein detection

Journal Highlight: CE with contactless conductivity detection for the quantification of fluoride in lithium ion battery electrolytes and in ionic liquids

Date: Mar 13, 2017

Author: separationsNOW

German chemists have coupled contactless conductivity detection with capillary electrophoresis to determine fluoride concentrations in lithium-ion battery electrolytes.

Read More thumbnail image: Journal Highlight CE with contactless conductivity detection for the quantification of fluoride in lithium ion battery electrolytes and in ionic liquids

Journal Highlight: Mass spectrometric based approaches in urine metabolomics and biomarker discovery

Date: Mar 6, 2017

Author: separationsNOW

This review discuss various mass spectrometry-based techniques for detecting disease biomarkers in urine, including combining mass spectrometry with chromatography and electrophoresis.

Read More thumbnail image: Journal Highlight Mass spectrometric based approaches in urine metabolomics and biomarker discovery

Mirror, mirror on the capillary: Enhancing fluorescence detection with a silver mirror

Date: Feb 20, 2017

Author: Jon Evans

Chinese scientists have increased the sensitivity of LED-based fluorescence detection by coating one side of the detection window with a silver mirror to reflect fluorescent light.

Read More thumbnail image: Mirror mirror on the capillary Enhancing fluorescence detection with a silver mirror
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