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Comprehensive Chromatography in Combination with Mass Spectrometry

Date: Aug 26, 2011

Author: Luigi Mondello

This book provides a detailed description of various multidimensional chromatographic separation techniques. The editor first provides an introduction to the area and then dives right into the various complex separation techniques. While still not used routinely comprehensive chromatography techniques will help acquaint the readers with the fundamentals and possible benefits of multi-dimensional separations coupled with mass spectrometry. The topics include a wide range of material that will appease all...

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Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites, 4th Edition

Date: Aug 24, 2011

Author: Hans H. Maurer, Karl Pfleger, Armin A. Weber

The world's most comprehensive reference for forensic toxicologists is keeping pace with recent developments in clinical toxicology in its new release: Another 800 new spectra have been added to this gold standard, including novel designer drugs and a broad range of AIDS therapeutics, for a total of 8,650 clinically relevant substances, including 5,200 metabolites. The print edition contains a comprehensive listing of all compounds in order of molecular mass, showing a reference mass spectrum as well as...

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Pharmaceutical Anti-Counterfeiting: Combating the Real Danger from Fake Drugs

Date: Aug 12, 2011

Author: Mark Davison

This book overviews and integrates the business and technical issues that pharmaceutical companies need to know in order to combat the major global problem of counterfeit medicines. In addition to discussion of the problems, the author Davison addresses analytical techniques scientists use to detect counterfeits and presents some possible solutions to the threat of counterfeit medical products. Coverage moves from basic overview of the problem, costs / risks to consumers (toxic products, mistrust of drug...

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Protein NMR Spectroscopy: Practical Techniques and Applications

Date: Jul 22, 2011

Author: Gordon Roberts, Lu-Yun Lian

Nuclear Magnetic Resonance (NMR) spectroscopy, a physical phenomenon based upon the magnetic properties of certain atomic nuclei, has found a wide range of applications in life sciences over recent decades. The dramatic advances in NMR techniques have led to corresponding advances in the ability of NMR to study structure, dynamics and interactions of biological macromolecules in solution under close to physiological conditions. This volume focuses on the use of NMR to study proteins. NMR can be used to...

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Illicit Drugs in the Environment: Occurrence, Analysis, and Fate using Mass Spectrometry

Date: May 13, 2011

Author: Sara Castiglioni, Ettore Zuccato, Roberto Fanelli

Illicit drugs are an emerging class of environmental contaminants and mass spectrometry is the technique of choice for their analysis. This landmark reference discusses the analytical techniques used to detect illicit drugs in wastewater and surface water, details how to estimate the levels of contaminants in the environment, and explores the behavior, fate, and toxic effects of this new class of contaminants, now a ubiquitous presence in wastewater and surface water. The book details how an estimate of...

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Platelet Proteomics: Principles, Analysis, and Applications

Date: May 10, 2011

Author: Ángel García-Alonso, Yotis Senis

The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics.  This chapter shows potential applications for platelet proteomics not yet carried out.  It includes examples of post-translational modifications (PTMs) analysis in platelets. The second part of the book focuses on the main research...

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Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and Applications

Date: Apr 26, 2011

Author: Mike S. Lee, Mingshe Zhu

This book examines the background, industrial context, process, analytical methodology, and technology of metabolite identification. It emphasizes the applications of metabolite identification in drug research. While primarily a textbook, the book also functions as a comprehensive reference to those in the industry. The authors have worked closely together and combine complementary backgrounds to bring technical and cultural awareness to this very important endeavor while serving to address needs within...

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Protein Purification: Principles, High Resolution Methods, and Applications, 3rd Edition

Date: Apr 8, 2011

Author: Jan-Christer Janson

This thoroughly revised and updated third edition provides an overview of the principles and methodology of the most frequently used biochemical separation techniques for proteins used today. Balancing theory, procedures, and applications, it offers professionals and students in biochemistry, organic chemistry, and analytical chemistry quick access to a wide range of important techniques, including: Gel filtration and ion exchange chromatography Affinity and covalent chromatography  Reversed phase...

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Analysis of Chemical Warfare Degradation Products

Date: Mar 15, 2011

Author: Karolin K. Kroening, Renee N. Easter, Douglas D. Richardson, Stuart A. Willison, Joseph A. Caruso

This book describes nerve agents and vesicants, their decomposition and their degradation products' chemistry as well as their toxicity including a list of detection techniques of nerve agents and their degradation products. This book will present their history, toxicity, comparison between different sample preparation methods, separation techniques, and detection methods all together in a short, easy to read book, tied together by a single group doing the writing and the editing to assure smooth...

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Encyclopedia of Analytical Chemistry: Applications, Theory and Instrumentation, Supplementary Volumes S1 - S3

Date: Feb 18, 2011

Author: Robert A. Meyers

The new 3-Volume Supplementary Set for Encyclopedia of Analytical Chemistry contains 95 new articles (published online in Encyclopedia of Analytical Chemistry (EAC) from 2008 – 2010), covering subjects which have achieved particular prominence and distinction since the print publication of EAC in 2000. The new 3 Volume Set includes advances in applications and theory ranging from mass spectrometry, atomic, infrared, Raman and X-ray spectroscopy, to nuclear magnetic resonance and...

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