The application of ICP-MS for the characterization of single nanoparticles in biological and environmental water samples

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Latest webinar from Agilent Technologies

The application of ICP-MS for the characterization of single
nanoparticles in biological and environmental water samples


Broadcast on November 14, 2017
This webinar is now available on-demand.
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Engineered nanomaterials (ENMs) used in various applications can improve the performance of many consumer and industrial products, for example in food and agriculture, personal care products, paints and coatings, solar power, water treatment and medicine. The production volume of ENMs has increased rapidly over the past decades due to new applications. The growing use of ENMs has raised concerns about their potential implications to the environment and human health. Over the past decade, increasingly more information has become available regarding the potential environmental implications of ENMs, including the estimates of the release of ENMs from products; the fate-and-transport of ENMs between different environmental compartments after release; the long-term behavior of ENMs in environment compartments and organisms; the toxicity of different ENMs; the sensitivity of different species to ENMs; potential human exposure to ENMs and their behavior in the human body. However, a major challenge has been the development of analytical techniques to detect their presence and determine their concentration in water and biological tissues.

In this webinar, the use of single-particle inductively couple plasma – mass spectrometry (sp-ICP-MS) as an emerging analytical technique for this novel class of materials will be presented. Dr. Keller has been working on the environmental applications and implications of nanotechnology for over a decade. Recently he received an Agilent Thought Leadership Award, in recognition of his contributions to the use of nanotechnology in agriculture. In addition to presenting the application, Dr. Keller will discuss the approach used to prepare the samples, optimize the detection, and interpret the results.

For Research Use Only. Not for use in diagnostic procedures

Key Learning Objectives:

  • Definition of engineered nanomaterial
  • Typical applications of engineered nanomaterial that are environmentally relevant
  • Approach used to prepare water and biological tissue samples for sp-ICP-MS analysis
  • Calibration
  • Optimization of detection of single nanoparticles
  • Interpretation of results

Who should attend:

  • Contract lab staff working on emerging contaminants
  • Industry lab staff working with nanomaterials (e.g. nanomedicine, food and agriculture, paints and coatings, personal care products)
  • Government lab staff working on emerging contaminants
  • Regulators interested in new methods for nanomaterials
  • Researchers working with nanomaterials (e.g. nanomedicine, food and agriculture, paints and coatings, personal care products)

   Your Presenter

Arturo Keller

Arturo A. Keller

Professor of Biogeochemistry
Bren School of Environmental
Science and Management
University of California, Santa Barbara

Arturo Keller: Biography

Dr. Keller received his M.S. and Ph.D. degrees in Civil and Environmental Engineering from Stanford University. He holds a B.S. in Chemical Engineering and a B.A. in Chemistry from Cornell University. Dr. Keller has over 30 years of experience in projects involving wastewater treatment, hazardous waste handling and management, pollution prevention and minimization, recycling and process modifications to reduce emissions. He is currently a Professor at the University of California in Santa Barbara, teaching at the graduate-level Bren School of Environmental Science and Management. His research interests include fate and transport of organic pollutants, as well as the development of innovative remediation technologies and pollution management strategies. He has published over 200 peer-reviewed papers.

Dr. Keller is co-Director of the NSF and USEPA funded UC Center for the Environmental Implications of Nanotechnology (CEIN), funded for 10 years for a total of $48M, which is dedicated to providing key information for addressing and managing any risks that may arise during the use of nanotechnology. Dr. Keller leads the group studying fate & transport, exposure and life cycle assessment of nanomaterials. In addition, Dr. Keller has developed several applications of nanotechnology to treat contaminated water sources and soils. In recognition of his contributions in this area, in 2015 Dr. Keller received the Agilent Thought Leadership award.

Dr. Keller is also a co-Director of the USEPA funded Chemical Life Cycle Collaborative, which seeks to develop a framework to make early predictions of the life-cycle implications of a new chemical or material, based on the chemical structure, applications and use characteristics. This $4.8M grant began in 2014.


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