Development and evaluation of microwave‐assisted and ultrasound‐assisted methods based on a quick, easy, cheap, effective, rugged, and safe sample preparation approach for the determination of bisphenol analogues in serum and sediments

Skip to Navigation

EarlyView Article

  • Published: Nov 9, 2017
  • Author: Shanjun Song, Mingwu Shao, Weihua Wang, Yajuan He, Xinhua Dai, Huiyu Wang, Liliang Liu, Feng Guo
  • Journal: Journal of Separation Science

Abstract

Microwave‐ and ultrasound‐assisted methods based on a quick, easy, cheap, effective, rugged, and safe sample preparation approach followed by high‐performance liquid chromatography with tandem mass spectrometry were developed for the simultaneous determination of eight bisphenol analogues in serum and sediment. The developed methods provided satisfactory extraction efficiency for the energy provided by microwaves and ultrasound. Compositions of commercial sorbents (primary secondary amine, MgSO4, octadecyl‐modified silica, and graphitized carbon black) were evaluated. The ultrasound‐assisted method was suited for serum using primary secondary amine, MgSO4, and octadecyl‐modified silica as sorbents and a mixture of hexane and ethyl acetate as extraction solvent. The microwave‐assisted method worked better for sediment with tetrahydrofuran and methanol as solvents and primary secondary amine, MgSO4, octadecyl‐modified silica, and graphitized carbon black as sorbents. Other experimental parameters, such as extraction temperature and time, were also optimized. The inter‐ and intraday relative standard deviations ranged from 2.7 to 5.5%. The limits of detection were between 0.1 and 1.0 ng/mL for serum and between 0.1 and 0.5 ng/g dry weight for sediment. The proposed methods were successfully applied to seven sediment and 20 human serum samples. The results showed that the developed methods were practical for the analysis and biomonitoring of bisphenols in sera and sediment.

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Most Viewed

Copyright Information

Interested in spectroscopy? Visit our sister site spectroscopyNOW.com

Copyright © 2017 John Wiley & Sons, Inc. All Rights Reserved