.... http://www.separationsNOW.com/coi/cda/landing.cda?type=Feature&chId=8 http://www.separationsNOW.com/coi/cma/download.cma?imageType=RssLogo&contentType=Feature&siteId=2&chId=8 http://www.separationsnow.com/ http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=23220&type=Feature&page=1 German scientists have developed a new self-modelling factor analytical method for extracting pure component spectra and the associated concentration profiles from a set of spectroscopic measurements. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=23163&type=Feature&page=1 Pistachio nuts can harbour deadly toxins, but detecting those toxins is far from easy. The answer, say Iranian scientists, is to try a bit of PARAFAC. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=23074&type=Feature&page=1 A Mexican scientist has developed an algorithm based on standard deviation optimization (scatter minimization) to determine the charge state and molecular weight of single proteins from average ESI-MS data. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=23023&type=Feature&page=1 Using functional data mining with electrophoresis, liquid chromatography and mass spectrometry, German scientists have analysed the proteome of the bacterium <i>Helicobacter pylori</i>. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22974&type=Feature&page=1 Using their previous experimental studies as a foundation, two German biomolecular engineers have built a model that can accurately predict retention times in ion exchange chromatography, albeit only for two proteins at present. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22841&type=Feature&page=1 German scientists have developed a new software tool, called lipID, for identifying glycerophospholipids, glycosphingolipids, fatty acids and small oligosaccharides in mass spectra. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22840&type=Feature&page=1 This review details the latest achievements in employing principal component analysis, a multivariate statistical technique, to evaluate chromatographic retention data. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22801&type=Feature&page=1 Due to an unusual ageing step, in which it is heated for a number of years, Madeira wine has an unusually rich and complex aroma, which offered a host of challenges to a team of Portuguese analytical chemists. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22738&type=Feature&page=1 Using GC-MS combined with a chemometric method named alternative moving window factor analysis, Chinese scientists have analysed the essential oils in various different types of mandarin orange. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22736&type=Feature&page=1 By devising new local centrality measures, two South Korean scientists have examined two recent yeast protein-protein interaction networks using 40 different centrality measures. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22685&type=Feature&page=1 Irish whiskey is full of both alcohol and numerous flavor-providing compounds, which is exactly why people drink it. It's also why scientists have found it so difficult to analyse. Until now, that is. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22524&type=Feature&page=1 This review of proteomics data repositories identifies freely available, centralized data resources that disseminate or store experimental MS data and results, with an emphasis on resources that may be of particular interest to yeast researchers. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22523&type=Feature&page=1 US engineers have developed a new nonlinear partial least squares algorithm called 'Quadratic Fuzzy PLS', which combines the outer linear Partial Least Squares and the Takagi-Sugeno-Kang fuzzy inference system. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22502&type=Feature&page=1 When are identical paracetamol pills not identical: when they're produced via different synthesis pathways. To try to distinguish between these different pathways, European researchers were forced to turn to impure thoughts. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22396&type=Feature&page=1 Croatian scientists have used sparse component analysis to perform a blind decomposition of mixtures of mass spectra into pure components, wherein the number of mixtures is less than the number of pure components. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22370&type=Feature&page=1 Croatian chemical engineers have developed a signal prediction model in gradient elution ion chromatography, based on a retention model and generalized logistic peak shape function. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22329&type=Feature&page=1 How do you protect valuable, historical books from degrading and falling apart? For a team of British and Slovenian researchers, the answer can be found in multivariate statistics. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22266&type=Feature&page=1 British scientists have combined MALDI-MS and LC-MS with artificial neural networks to develop a method for identifying protein and peptide biomarkers associated with the administration of recombinant human growth hormone. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22234&type=Feature&page=1 Building on their previous research, a team of US chemists has developed a new automated method for resolving peaks across large sections of, or even entire, GC × GC-TOFMS chromatograms, which they tested on diesel and urine samples. http://www.separationsNOW.com/coi/cda/detail.cda?chId=8&id=22242&type=Feature&page=1 Taken from the Special Issue of the <I>Journal of Chemometrics</I> which is dedicated to Professor Richard A. Harshman who died early last year.