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By designing a stationary phase with a similar structure to ice cream, Chinese chemists have developed a novel ion-exchange chromatography process for isolating the cellular fuel molecule adenosine triphosphate. [December 10, 2007] |
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Using a weak cation-exchange column, Chinese researchers have developed an SPE-HPLC method for simultaneous determination of adrenergic receptor antagonists, which are used to treat high blood pressure, in human plasma. [December 3, 2007] |
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Canadian researchers have developed a simple process for producing lentiviral vectors, which are commonly employed as gene delivery vehicles, using scaleable production and purification methodologies, including heparin affinity chromatography. [November 26, 2007] |
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Italian analytical chemists have developed an ion chromatography (IC) technique for analysing ice cores and used it to help produce the longest and most detailed record ever of ancient atmospheres. [November 12, 2007] |
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British researchers have developed a method for quantitative protein profiling utilising multidimensional liquid phase protein separations, comprising ion exchange chromatography and RP capillary chromatography, with stable isotope labelling. [November 5, 2007] |
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Italian chemists have prepared samples of mesoporous silica functionalised with carboxylic groups and shown that they make an effective stationary phase for the cation-exchange chromatography of heavy metals. [October 22, 2007] |
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Chinese separation scientists have shown that ion exchange chromatography can fold and purify recombinant proteins much faster and more effectively than conventional protein folding techniques. [October 8, 2007] |
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Portuguese chemical engineers have used a gradient simulated moving bed (SMB) model to analyse the performance of the salt gradient ion-exchange SMB process, based on literature data for the linear adsorption of proteins. [October 1, 2007] |
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Romanian researchers have used a reliable, low-cost and sensitive ion pair liquid chromatography/fluorescence (IPLC/FLD) method to determine levels of the antihistamine drug loratadine in human plasma samples. [September 24, 2007] |
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US chemists have combined anion-exchange chromatography and amperometric detection to develop a quick and sensitive method for identifying whether gelatin is derived from cow, pig or fish. [September 10, 2007] |
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Belgian researchers have evaluated 'extended polarity' reversed liquid chromatography phases, which were developed specifically to retain polar compounds, in terms of their ability to analyse plant metabolites. [September 3, 2007] |
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US researchers have adapted a technique for detecting amino acids in biological fluids, which involves using liquid chromatography and mass spectrometry with perfluorinated acids as ion-pairing agents, to time-of-flight MS. [August 27, 2007] |
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A team of Dutch biotechnologists has shown that generating a wide-ranging pH gradient in an ion exchange chromatography column produces a highly effective tool for optimising protein purifications. [August 13, 2007] |
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German researchers have shown that the attachment location of a fluorescent probe on the surface of a protein can have a strong effect on the retention of the protein-dye conjugate in ion-exchange chromatography. [August 6, 2007] |
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Chinese environmental scientists have developed a method for quantifying sugars, alditols, and alcohols in tobacco, based on high-performance anion-exchange chromatography, and used it to classify different tobacco products. [July 23, 2007] |
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By taking advantage of a novel form of ion exchange chromatography, researchers from the pharmaceutical giant AstraZeneca have developed an efficient method for producing relatively large amounts of purified plasmid DNA. [July 9, 2007] |
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This review focuses on recent developments in the high-performance chelation ion chromatography of trace metals, while giving important information on the fundamental parameters controlling the chelation sorption mechanism, including type of chelating group, stability constants, kinetics, and column temperature. [July 2, 2007] |
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A high-throughput protein purification strategy using polycationic tags and cation exchange chromatography has been developed. In order for the strategy to be useful both for soluble and less soluble proteins, a denaturating agent, urea, was used in all purification steps. [June 25, 2007] |
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A team of Swedish biochemists and molecular biologists has combined ion-exchange chromatography and two-dimensional electrophoresis to create a novel method for assessing marine pollution. [June 11, 2007] |
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The separation of several insect oostatic peptides was achieved by using CEC with a strong-cation-exchange stationary phase in a fused-silica capillary column. [June 4, 2007] |
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