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Bringing Mass Spec to the Masses - From niche tool to necessity: the history of MS in the pharmaceutical industry Bringing Mass Spec to the Masses - From niche tool to necessity: the history of MS in the pharmaceutical industry
This article on the history and impact of mass spectrometry in the pharmaceutical industry is the first in a new series for Pharmaceutical Formulation & Quality, the premier source of news and information for pharmaceutical and biopharmaceutical industry professionals. [October 14, 2009]
Welcome to the Year of Education in Separation Science, in Conjunction with Chromedia! Welcome to the Year of Education in Separation Science, in Conjunction with Chromedia!
The Year of Education came about through discussions between 3 professors who actively teach chromatography. The first activity in the Year of Education will be a series of free educational webinars, run in conjunction by separationsNOW and Chromedia. In the first webinar, Professor Harold McNair will give an interactive lecture on the basics of gas chromatography. Find out more at separationsNOW.com/chromedia. [October 1, 2009]
Mass Spectral Libraries - Reproducibility in EI, API and Tandem Mass Spectrometry Mass Spectral Libraries - Reproducibility in EI, API and Tandem Mass Spectrometry
A number of publications have recently appeared in which attempts have been made to determine the reproducibility of tandem mass spectra libraries. For several decades libraries of EI spectra have been used successfully for compound identification, especially from GC-MS data, while, in contrast, many difficulties seem to be present in trying to achieve the same success for tandem mass spectrometry data. This short essay attempts to answer the question of why this difference should occur, what is it about EI spectra which are so reproducible over a wide variety of instruments, laboratories and over long periods of time and what methods have been tried to improve the success rate of the latter. [April 15, 2009]
Chromedia Chromatogram Generator Tool Chromedia Chromatogram Generator Tool [registered users only]
This tool is brought to you by Chromedia - a new on-line community for today's practical chromatographers. Jeroen Billen and Gert Desmet of the Vrije Universiteit of Brussels have developed with Peter Schoenmakers an optimization tool for chromatographers. [April 2, 2009]
Chromedia Resolution Equation Tool Chromedia Resolution Equation Tool [registered users only]
This tool is brought to you by Chromedia - a new on-line community for today's practical chromatographers. The tool has been created to help you intuitively understand the resolution factor. [April 2, 2009]
Modern Supercritical Fluid Chromatography Modern Supercritical Fluid Chromatography [registered users only]
This primer provides an overview of the history and applications of Supercritical Fluid Chromatography, including comparisons with HPLC and GC. It was written for separationsNOW.com by Professor Larry T. Taylor of Virginia Polytechnic Institute and State University, USA. [July 29, 2008]
Introduction to HPLC Introduction to HPLC [registered users only]
This free tutorial, the second in a series brought to you by earl, provides a thorough introduction to HPLC. Learn the basics, including: a brief history of HPLC; comparison with Gas Chromatography; an introduction to the Chromatograph and Chromatogram; an overview the main principles of separation; and an explanation the uses and applications of the different "modes" of chromatography. [November 1, 2007]
Fundamental LC-MS Fundamental LC-MS [registered users only]
This free tutorial, brought to you by earl provides an introduction to the various LC-MS techniques. [September 11, 2007]
A practical guide to nano-LC troubleshooting A practical guide to nano-LC troubleshooting [registered users only]
In this Journal of Separation Science article, the most important issues of capillary LC systems are discussed, including void and dead volumes, leakages, sample injection, and a multidimensional LC approach. Practical advice on system diagnosis is presented, with examples. [August 7, 2007]
An introduction to on-line LC-NMR An introduction to on-line LC-NMR [registered users only]
In this free chapter from "On-line LC-NMR and Related Techniques" Klaus Albert introduces the theory and practice of this interesting technique [October 1, 2005]
Chiral separation and detection by chromatography and capillary electrophoresis Chiral separation and detection by chromatography and capillary electrophoresis [registered users only]
This free chapter from "Chiral Pollutants: Distribution, Toxicity and Analysis by Chromatography and Capillary Electrophoresis" introduces chirality and chiral separations with particular references to chiral pollutants [October 1, 2005]
An introduction to HPLC An introduction to HPLC [registered users only]
In this free chapter from "Practical High-Performance Liquid Chromatography", Veronika Meyer introduces the basis of HPLC [October 1, 2005]
A Primer on LC/NMR/MS A Primer on LC/NMR/MS
In this primer, Steve Down provides a detailed look at how these analytical techniques have been coupled together to provide an extremely powerful bioanalytical tool. [September 28, 2005]
For more education articles, see the links directory.... For more education articles, see the links directory....
Many external websites have excellent tutorials, application notes and "hints & tips" features. We've collected some of these in our links directory - click on "links" at the top of the page. [October 1, 2001]