Induction of a pluripotent state in somatic cells through nuclear reprogramming has ushered in a new era of regenerative medicine. However, heterogeneity and varied differentiation potentials among induced pluripotent stem cell (iPSC) lines challenge our ability to identify and isolate functionally defined cell populations for disease modeling, drug discovery, and patient therapies. Thus, there is an urgent need to develop non-genetic methods for isolating more homogeneous, functionally defined iPSCs.

Tuesday, February 28, 2012

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Traditionally, targeted peptide quantification studies have used a triple quadrupole (QQQ) mass spectrometer because of their high throughput capabilities and high sensitivity, allowing for large numbers of proteins to be quantified in a single LC/MS experiment. However, the transition from discovery to targeted verification and quantification can still be slow and cumbersome due to the transition between different mass spectrometer platforms.

In this webinar, new approaches to peptide-targeted quantification using high-resolution and accurate mass (HR/AM) mass spectrometry are introduced, together with the new Q Exactive high-performance benchtop quadrupole-Orbitrap LC-MS/MS.

This webinar has been recorded
and is now available on-demand.

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