Combine Data Accuracy and Sample Analysis Precision for an Optimized Pharmaceutical Lab
Thursday, February 2, 2012 - 16:00 UTC
Learn how to meet the application needs of the pharmaceutical industry with easy to use, innovative and compliant analysis techniques. Whether performing multi-component analysis with the Agilent 8453 UV-Vis, taking advantage of the workflow improvements with fiber optic accessories on the Cary 60, or utilizing the extremely compact size, and snap and go sampling interfaces of the Cary 630 FTIR, get the versatility and reliability you need for pharmaceutical compliance.
Revolutionize Routine FTIR Applications with the new Agilent Cary 630 FTIR
Agilent Technologies is revolutionizing routine FTIR analysis from sample handling to data interpretation. In addition to delivering increased instrument performance, additional instrument sampling capability, hardware robustness, software ease-of-use, Agilent FTIR systems reduced the amount of time spent analyzing samples. New applications, solutions, and accessories will be discussed to further increase your labs. Agilent profiles the Michelson interferometer as a way to obtain the best results from this innovative technology.
Supercritical Fluid Chromatography: Past, Present and Future
In this webinar, the use of CO2 as a major as well as a minor mobile phase constituent is discussed in terms of chromatographic performance; and a comparison is made with the recent developments in LC. Starting with a step by step presentation of the fundamental aspects and features of using super- and subcritical fluids in chromatography, a series of examples is given to demonstrate its strong and weak points. In addition, method development in SFC is discussed and generic conditions for the analysis of achiral and chiral solutes are presented. Hyphenation with ELSD and MS is also highlighted.
Microwave Plasma - Atomic Emission Spectroscopy, a Revolutionary New Technique and Plasma Source that Increases Performance While Eliminating Expensive Gas Requirements
In the past 10 years, analytical chemistry has left the laboratory and headed out to the field. New applications along with technological advancements have fostered the development of a new group of analytical instruments. Microwave Plasma - Atomic Emission Spectroscopy (MP-AES) represents a completely new elemental analysis technique that has been designed to improve analytical performance and productivity, while decreasing operating costs by eliminating the flammable and/or expensive gas requirements used in typical elemental analysis techniques. This webinar presents an overview of the MP-AES technique, hardware, software and its capabilities. Performance is demonstrated for a range of sample types including examples from the geochemical, petrochemical, agricultural and environmental areas.
Use of FTIR spectroscopy in and out of the laboratory: questions answered...
The webinar provides examples of applications which are currently being deployed as field based FTIR measurements and explains how these techniques, developed in the lab, have been adapted for field measurement.
Why use signal-to-noise as a measure of MS performance when it is often meaningless?
In the past, the signal-to-noise of a chromatographic peak determined from a single measurement has served as a convenient figure of merit used to compare the performance of two different MS systems. The evolution in the design of mass spectrometry instrumentation has resulted in very low noise systems that have made the comparison of performance based upon signal-to-noise increasingly difficult, and in some modes of operation impossible. This is especially true when using ultra-low noise modes such as high resolution mass spectrometry or tandem MS; where there is often no ions in the background and the noise is essentially zero.
Intelligent System Emulation Technology: How to overcome pitfalls in the transfer of methods between different LC instruments
Instrument-to-instrument method transferability is an important topic for all laboratories throughout all industries, where HPLC and UHPLC methods are transferred between different departments and locations with different LC instruments. This webinar explains which parameters affect the instrument-to-instrument HPLC and UHPLC method transferability and discusses the different solutions including Agilent's new Intelligent System Emulation Technology (ISET) in the 1290 Infinity LC.
New Molecular Spectroscopy Solutions to Improve Life Science Lab Capability and Productivity
From spectroscopic measurements of fast kinetic processes to plug-and-play versatility to robust and dependable hardware, Agilent meets your molecular spectroscopy needs. In this interactive webinar, Agilent product specialists will discuss the newly released Cary 60 UV-Vis spectrometer, featuring unrivaled Xe flashlamp technology and fiber optic capabilities, productivity enhancing sampling techniques, and life science applications such as measuring micro-volume and cold (4oC) samples, which are usually difficult or impossible using conventional sampling techniques.
A Picture is Worth a Thousand Words: FTIR Microscopy & Imaging Can Help You Solve Your Complex Analytical Problems
This webinar presents the basics of FTIR microscopy theory, the use of FTIR microscopes and imaging systems, and discusses some routine applications in materials, polymer, biological and biomedical sciences. We also illustrate how FTIR microscopy and imaging can quickly provide solutions to complex analytical problems.
High-Performance LC-Based 'Well-Characterized Biologics'
Different LC-based techniques are applied to characterise biotherapeutics, or to prove protein identity, in order to fulfill complex regulatory requirements. The presenters of this webinar discuss the limitations of LC techniques when characterizing New Biological Entities or 'NBEs'. They also describe why UHPLC on the 1260 bio-inert LC instrument, in combination with small particle columns technology, is an efficient approach to increase productivity and resolution: not only for small molecules, but also for peptides and proteins.
Identify, Confirm, Solve, Explore with FTIR
This webinar presents: basics of FTIR theory; the appropriate selection of sampling accessories for the analysis of liquids, solids and gases; examples of their use in many routine applications. Topics covered include: spectral interpretation; a guide to quantitative analysis; generation and implementation of spectral libraries for the rapid authentication of raw materials and finished products.
Clearly Better - The New Atomic Spectroscopy Portfolio from Agilent
Agilent Technologies & Varian, Inc. are now one company. This series of web events offers a portfolio overview, specific instrument technology updates and will highlight applications which utilize the new portfolio of technologies, including AA, ICP-OES and ICP-MS products. Attend one or more of these online events to learn about the expanded atomic spectroscopy portfolio and solutions now available from Agilent Technologies.
QuEChERS 101: The Basics and Beyond
In this webinar, we discuss in detail the QuEChERS extraction procedure from the point of product arrival through extraction, dispersive SPE and on to analysis. Factors that affect recovery and increase throughput will be presented in addition to future applications for QuEChERS, reaching far beyond pesticides in food products. What you will learn: new users will gain a basic understanding of the QuEChERS method and its benefits; experienced users will learn about new advances and optimization of the QuEChERS methodology; discover the unique feature and advantages of the Agilent QuEChERS kits.
GC/MS/MS: Five Reasons to Upgrade from GC/MS
International regulations for Food Safety have driven an increased use of GC/MS/MS for trace level pesticide residue analysis. Other specialty applications such as nitrosamines (environmental; drinking water) and THC-COOH (toxicology; hair) have also drawn attention to the selectivity and consistent sensitivity of this technique. These success stories have caused routine users of GC/MS to evaluate the benefits of MS/MS. Please join us to learn the technical and practical benefits of GC/MS/MS. You might realize that there are more than five reasons to adopt the power of quadrupole MS/MS!
Improving Data Quality in ICP-MS
In the first webinar of this series, Ed McCurdy and Steve Wilbur assess the fundamental performance of He mode in removing spectral interferences in ICP-MS, thereby making such qualifier ions available for evaluation of data quality. In second webinar Ed and Steve present data demonstrating the use of qualifier ions to improve ICP-MS data quality in complex sample matrices, by confirming the measured result from the primary isotopes.
How to Increase Lab Performance with Agilent Ultra High Pressure Valve Solutions - Reducing the Time for Developing Optimal Methods
In this event, Dr. Mattias Pursch (Technology Leader, Liquid Chromatography, Dow Chemical) highlight the implementation of rapid method development using automated column and solvent screening for practical applications of industrial LC separations. Dr. Michael Frank (Product Manager, Agilent Technologies) further the discussion on automated method development by introducing the latest developments including utilizing the new Agilent 1290 Infinity LC system for additional LC capabilities to achieve infinite separation conditions.
He Mode Interference Removal for Spectral Clarity and Multi-Isotope Confirmation
The contribution that collision/reaction cells (CRC) can make to improving ICP-MS data quality by removing spectral interferences has been well documented. Similarly the potential for data quality to be degraded by the creation of new interferences or the loss of analyte sensitivity by reaction has also been widely discussed. However, the use of an inert cell gas (helium mode) and interference removal using kinetic energy discrimination (KED) not only avoids these problems, but also has the added benefit that it can effectively remove any polyatomic interference, rather than being suitable only for interferences which react with the chosen cell gas. This avoids the issue of incomplete removal of unreactive interferences, and allows helium (He) mode to be considered as a "universal" cell mode, being applied to almost all analytes in virtually any sample type.
Latest Advances in HPLC & UHPLC: The Last Word
Are you asked to save solvents, go for more sensitivity or higher resolution?
Join our panelist discussion of the latest LC technologies and what this means to you as a chromatographer or mass spectrometrist. Introducing the Agilent 1290 Infinity LC.
Your answer is finally here.
Redefining ICP-MS Analysis; Higher Matrix Levels, Simpler Operation; Better Removal of Interferences:
The Extraordinary New 7700 Series ICP-MS
After 20 years, ICP-MS technology has reached a stage of development where improvements are incremental, rather than revolutionary. Nevertheless, there were aspects of existing instrumentation where performance could clearly be improved, such as increasing matrix tolerance, improving the removal of interferences, and simplifying routine operation. All of these areas have been the focus of research and development at Agilent Technologies, leading to the introduction of the 7700 Series, the most significant new ICP-MS product launch for many years.
This live online seminar provides a comprehensive introduction to the very latest ICP-MS developments, as embodied in the 7700 Series ICP-MS; brand new technology which redefines the way routine and research labs do ICP-MS, introducing unparalleled performance, from the smallest commercial ICP-MS ever made.
Pharmaceuticals and Personal Care Products in Water, Soil, Sediment, and Biosolids by HPLC/MS/MS - EPA Method 1694
This complimentary seminar focuses on the utilization of HPLC/MS/MS within EPA Method 1694 guidelines. Since the discovery of persistent pharmaceuticals in wastewater and their widespread occurrence, numerous papers have appeared on the analysis of these compounds. EPA has established a method, EPA 1694, to evaluate these compounds in many environmental matrices. We have tested this EPA method and report on our results. Thus, an analytical methodology for screening and confirming the presence of 74 pharmaceuticals in water samples was developed using a triple quadrupole mass spectrometer. The method was developed following the guidelines in EPA Method 1694. Four distinct chromatographic gradients and LC conditions were used according to the polarity and extraction of the different pharmaceuticals. Positive and negative ion electrospray were used with two MRM transitions (a quantifier and a qualifier ion for each compound), which adds extra confirmation in this methodology compared with the EPA method. Linearity of response of 3 orders of magnitude was demonstrated (r2 > 0.99) for all the pharmaceuticals studied. The analytical performance of the method was evaluated for one wastewater sample collected in Boulder Creek, Colorado; positive identifications for carbamazepine and diphenhydramine were found for this sample using the methodology developed in this work. This study is a valuable indicator of the potential of the QqQ for routine quantitative multi-residue analysis of pharmaceuticals in water and wastewater samples.
Attendees will benefit from this live session, which presents the results of using HPLC/MS/MS to meet EPA Method 1694 guidelines.
Tripling productivity with ICP-MS - Innovative Optimization Techniques
From a performance standpoint (sensitivity, accuracy, linearity), ICP-MS is the undisputed technique of choice for elemental analysis in most applications. However, for applications which don't require state of the art performance, ICP-OES typically has an advantage in productivity in terms of samples run per day. The factors which have constrained the productivity of ICP-MS have included diluting samples to accommodate limited dissolved solids tolerance, gas switching and stabilization times for collision/reaction cell instruments and inefficient sample uptake and rinseout systems. By systematically addressing each of these limitations, Agilent has been able to reduce the typical run to run time for collision cell ICP-MS from 5-6 minutes per sample to a minute or less without adversely impacting the performance. Discussion of the various optimization techniques with example applications and results will be included.
Attendees will benefit from this live discussion with one of Agilent's ICP-MS Specialists. Hear our expert offer best practices in ICP-MS to help you achieve better results in less time.
Advances in HPLC Method Development: 3 Steps to the Best HPLC Methods
Developing the 'best' LC method is often a complex task that requires skill and patience. New techniques and technologies are available to aid in streamlining the process of developing an LC separations method thereby reducing the necessary trial and error analyses.
This live, on-line series offers three steps to creating the 'best' methods and focuses upon the core fundamentals in method development, choosing appropriate stationary phases, and automating method development in your lab saving significant time and effort.
After attending these educational sessions on method development, developing your own 'best' method is just one LC analysis away!.
Got Mass? Fast LC and LC/MS: Answers to your lab's demanding questions
This complimentary 3-part seminar series focuses on utilizing RRLC with Single Quad, Triple Quad and TOF mass spectrometry, highlighting the advantages of using sub-two micron particle technology for high resolution, fast chromatography coupled to mass spectrometers with the latest technological advances. In addition, the large data pools generated from fast analysis requires significant time for data review. Automated data analysis software accompanying the latest instrument technologies will be illustrated for the transition of great data into great discoveries.
Best Practices and Practical Tips for Rapid Resolution LC
This complimentary 3-part series is an excellent resource for all LC scientists. The seminar series offers valuable technical content and shows you how to get LC separations better, faster and easier.
Utilizing Sub-2µm Particles to Optimize HPLC Methods
This complimentary four part series is an excellent resource for any LC scientist. The on-demand event is a must for all who want LC separations better, faster and easier.
After completing this workshop, you will be able to:
This technical resource gives you the tools to increase efficiency and speed in your lab workflow by 3 - 20 times compared to conventional 5 micron and 3 micron particle technology.
View an archive of all our webinars at:
www.spectroscopyNOW.com/agilentwebinars
