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[June 24, 2008]

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Supercritical Fluid Chromatography (SFC)

Advancements in SFC Performance from Sensitivity to Throughput

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Abstract

As SFC is gaining momentum as an up-and-coming mainstream chromatographic technique, it is important to better understand the fundamentals of this technique from the perspective of detection behavior.

In this webinar, Dr. Chen explains his group's effort in expanding the horizon of SFC applications outside of the pharmaceutical industry as well as understanding the unique behavior of MS and ELSD under SFC conditions. In addition, the significant improvement in UV detection sensitivity and its implication for method validation, and a multi-channel SFC system for high throughput screening is discussed in great detail.


Your Presenter

Rui ChenDr Rui Chen
Global Technical Support Manager
Thar Instruments


SFC MS Prep 100 Method Station II
SFC-MS Prep 100 Method Station II




Previous Webinars

SFC-MS: The State of the Art in 2009
Dr Andreas Tei

In this webinar, Dr Andreas Tei reviews the history and the fundamentals of SFC-MS, from the perspectives of ionization and SFC hardware. SFC's orthogonality to LC is demonstrated by a wide variety of real industrial applications, including structure elucidation, degradant characterization, metabolite identification, pharmacokinetic measurement, and mass-directed purification.

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Faster, More Efficient Chiral Separations with SFC
Thomas DePhillipo

Attend this webinar on SFC to learn how rhe superior resolving power of SFC has distinguished the technique from others when it comes to resolving structurally related compounds and isomers with greater efficiency.

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Chiral Separations using SFC: Analytical Applications from Discovery through Development
Peter Ridgway

In this webinar, Mr. Ridgway explains the fundamentals of supercritical fluids and Supercritical Fluid Chromatography, with a particular emphasis on enantio-selective separation.

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SFC-MS: From Analytical to Mass-Directed Purification
Dr. Rui Chen

In this webinar, Dr Rui Chen from Thar Instruments, reviews the history and fundamentals of SFC-MS from the perspectives of ionization and SFC hardware.

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Introduction to SFC
Dr. Rui Chen

In this webinar, Dr Rui Chen from Thar Instruments explains the fundamentals of supercritical fluids and Supercritical Fluid Chromatography, including the physical properties of supercritical CO2 and their implication in separation, the typical SFC hardware, and possible choices of detection.

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Thar Technologies, Inc.

www.tharsfc.com

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